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[Anesthetic implications in antiphospholipid syndrome. 2 clinical cases].

Rev Esp Anestesiol Reanim

May 1995

Servicio de Anestesiología y Reanimación, Hospital Universitario de Valme, Sevilla.

Anti-phospholipid syndrome, originally called anticardiolipin syndrome, is characterized by the presence of anti-phospholipid antibodies and a marked tendency to both arterial and venous thrombosis. The little information available on the implications of this syndrome for anesthesia derive from the recent description of the disease. We describe 2 patients, each with 1 of the 2 forms of antiphospholipid syndrome that have been described to date, and each needing surgery for a different reason.

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J Tenn Med Assoc

July 1992

Division of Maternal and Child Health, Tennessee Department of Health, Nashville.

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Oral contraceptive oestrogen and progestin potencies and the incidence of deep venous thromboembolism.

Int J Epidemiol

December 1990

Office of Epidemiology and Biostatistics, Food and Drug Administration, Rockville, MD 20857.

To assess possible differences in the incidence of venous thrombosis and pulmonary embolism associated with oral contraceptives of varying hormonal potencies, the authors conducted a retrospective cohort study in the 15-44 year old Michigan Medicaid population. Cohorts were defined by the progestin- and oestrogen-potencies of oral contraceptives in use at the time of follow-up as classified by an oral contraceptive potency scheme. Using the low-oestrogen-/low-progestin-potency formulations for reference (rate ratio = 1), adjusted rate ratios of 0.

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Unlabelled: The typical case present with a unilateral, atypical claudication with discrete oedema, occurring after repeated exercise. These paradoxical features of venous pain, aggravation with attacks, resolution after prolonged rest and the absence of arterial signs are suggestive of the disease. The syndrome may present as repeated calf thromboses or recurrent varicose veins suggesting some deep obstruction.

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