Continue development of endoscopic techniques of rinosinusal approach involves knowledge about the anatomy of this region, with a three-dimensional orientation before surgery, a therapeutic plan well thought, anticipating the gesture controller, taking into account the particularities of each case. Endoscopic surgical anatomic variants parts at this level can be well identified by imaging methods (CT, MRI). CT study of patients who are candidates for surgery Fess is on top, as the technique of choice. MRI is the imaging method to supply the CT data, providing a study carried out the normal anatomy and standard deviation of the numerous variants, single or in combination. This paper aims a randomized retrospective study of 120 MRI of the head and face region, to investigate and highlight the anatomical variations of structures at this level of impact and those with sinusitis etiopatologia, as well as those with operative risk (bleeding complications, ocular, vital risk) to determine the prevalence in the general population and have to compare the data with the literature. Using all sections (axial, sagittal and coronal) with the aid of different sequences (T1, T2, Flair and diffusion) allowed study of three-dimensional images of whole rhino-sinus-related pathology. Anatomic variations of surgical landmarks have investigated a wide range of expression, which are unique or associated with a complex architecture, with sufficient accuracy and visible on MRI. Their prevalence in the group studied was generally consistent with the literature studied.
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Am J Sports Med
January 2025
Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Background: Knee injuries resulting in purely cartilaginous defects are rare, and controversy remains regarding the reliability of chondral-only fixation.
Purpose: To systematically review the literature for fixation methods and outcomes after primary fixation of chondral-only defects within the knee.
Study Design: Systematic review; Level of evidence, 5.
Am J Sports Med
January 2025
Department of Orthopaedic Surgery, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea.
Background: Studies are still limited on the isolated effect of retear after arthroscopic rotator cuff repair (ARCR) on functional outcomes after the midterm period.
Purpose: To assess the effect of retear at midterm follow-up after ARCR and to identify factors associated with the need for revision surgery.
Study Design: Cohort study; Level of evidence, 3.
Eur J Hum Genet
January 2025
Institute of Bioinformatics, International Technology Park, Bangalore, 560066, India.
Mitochondrial membrane protein-associated neurodegeneration (MPAN) is a rare neurodegenerative disorder characterized by spastic paraplegia, parkinsonism and psychiatric and/or behavioral symptoms caused by variants in gene encoding chromosome-19 open reading frame-12 (C19orf12). We present here seven patients from six unrelated families with detailed clinical, radiological, and genetic investigations. Childhood-onset patients predominantly had a spastic ataxic phenotype with optic atrophy, while adult-onset patients were presented with cognitive, behavioral, and parkinsonian symptoms.
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January 2025
Division of Cardiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Myocyte disarray and fibrosis are underlying pathologies of hypertrophic cardiomyopathy (HCM) caused by genetic mutations. However, the extent of their contributions has not been extensively evaluated. In this study, we investigated the effects of genetic mutations on myofiber function and fibrosis patterns in HCM.
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January 2025
Cardiovascular Research Center, Rajaie Cardiovascular, Medical, and Research Center, University of Medical Sciences, Tehran, Iran.
Assessing myocardial viability is crucial for managing ischemic heart disease. While late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) is the gold standard for viability evaluation, it has limitations, including contraindications in patients with renal dysfunction and lengthy scan times. This study investigates the potential of non-contrast CMR techniques-feature tracking strain analysis and T1/T2 mapping-combined with machine learning (ML) models, as an alternative to LGE-CMR for myocardial viability assessment.
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