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Improved porosity promotes reendothelialization and smooth muscle remodeling in decellularized tissue-engineered vascular grafts.
Mater Today Bio
February 2025
Department of Vascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Decellularized tissue-engineered vascular grafts (dTEVGs) exhibit superior biocompatibility, anti-infection properties and repair potential, contributing to better patency and making them a more ideal choice for arteriovenous grafts (AVGs) in hemodialysis compared to chemically synthesized grafts. However, the unsatisfactory reendothelialization and smooth muscle remodeling of current dTEVGs limit their advantages. In this study, we investigated the use of elastase to improve the porosity of elastic fiber layers in dTEVGs, aiming to promote cell infiltration and achieve superior reendothelialization and smooth muscle remodeling.
View Article and Find Full Text PDFArterial switch operation: A surgical triumph with long-term management challenges.
Int J Cardiol Congenit Heart Dis
March 2024
Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Since the late 1980s, the standard approach for treating D-transposition of the great arteries has been the arterial switch operation (ASO), replacing the Mustard/Senning procedure. Although ASO has shown impressive long-term survival rates, recent case series have revealed late complications such as neoaortic dilation and coronary artery stenosis. New findings emphasize the need for comprehensive evaluation of coronary risk and a deeper understanding of the mechanisms leading to coronary artery stenosis and myocardial ischemia over the long term.
View Article and Find Full Text PDFThe Mickey Mouse Sign: A Novel Sign for a Compliant and Underactive Bladder Syndrome.
Cureus
October 2024
Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, PSE.
This article represents a unique CT-based sign called the Mickey Mouse sign in a diabetic female who presented with abdominal distension and mixed urinary symptoms. The CT scan showed that the bladder was massively dilated but compliant without impacting the upper urinary tract. The subtle clinical presentation and the impressive CT scan findings encouraged us to report this case as underactive bladder syndrome (UAB) is underreported and underinvestigated.
View Article and Find Full Text PDFAnesthetic Challenges in a Pediatric Patient With Chronic Kidney Disease Complicated by Dilated Cardiomyopathy Undergoing Non-cardiac Surgery.
Cureus
September 2024
Anesthesiology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Dilated cardiomyopathy (DCM), a primary myocardial disorder, manifests through the dilation of one or both ventricles, coupled with systolic and valvular dysfunction. Renal agenesis is a congenital condition characterized by the absence of one or both kidneys at birth. Unilateral renal agenesis, wherein one kidney is absent, can subtly evade detection due to the impressive adaptability of the remaining kidney, often preserving typical functionality.
View Article and Find Full Text PDFA Recursive Prediction-Based Feature Enhancement for Small Object Detection.
Sensors (Basel)
June 2024
School of Electronics and Information Engineering, Liaoning University of Technology, Jinzhou 121001, China.
Transformer-based methodologies in object detection have recently piqued considerable interest and have produced impressive results. DETR, an end-to-end object detection framework, ingeniously integrates the Transformer architecture, traditionally used in NLP, into computer vision for sequence-to-sequence prediction. Its enhanced variant, DINO, featuring improved denoising anchor boxes, has showcased remarkable performance on the COCO val2017 dataset.
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