Purpose: Behavioural, personal, psychological, sociodemographic, environmental, biological and childbearing factors have been associated with obesity among women. This study quantitatively explored the effects of these factors on predicting body mass index (BMI) in U.S. women using the International Classification of Functioning, Disability and Health (ICF) and determined the effectiveness of using the ICF with population-level data.
Methods: We used the ICF Core Sets for Obesity, and data from the 1999-2006 National Health and Nutrition Examination Survey (NHANES) in a sample of 8766 U.S. women to quantify the impact of all associated causal factors. Linear regression was used in the analyses.
Results: Body image perceptions (42%) was the most significant contributor, followed by hypertension (12%), general health condition (11%), diabetes/borderline diabetes (10%), arthritis (9%) and performing vigorous activity (9%).
Conclusions: To decrease obesity prevalence rates in U.S. women, obesity prevention and treatment programmes should parallel the contributory effects of its most significant causal factors of psychological, biological and behavioural. In addition, more research and data are needed to explore the relationship between BMI in women and the multiple influencing factors by going beyond the more frequently available information of age, gender, race, education, income and parity.
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http://dx.doi.org/10.3109/09638288.2010.505994 | DOI Listing |
Respir Res
January 2025
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Center for Chronic Disease Prevention and Control, Harbin Medical University, Harbin, 150081, People's Republic of China.
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease, influenced by both environmental and genetic factors. Single nucleotide polymorphism (SNP) in the human genome may influence the risk of developing COPD and the response to treatment. We assessed the effects of gene polymorphism of inflammatory and immune-active factors and gene-environment interaction on risk of COPD in middle-aged and older Chinese individuals.
View Article and Find Full Text PDFInt J Geriatr Psychiatry
January 2025
Division of Psychiatry, University College London, London, UK.
Introduction: While risk factor prevalence of individual risk factors for dementia varies between ethnic groups in New Zealand (NZ), it is not known whether the effect of these risks is the same in each group.
Methods: This retrospective cohort study identified incident cases of dementia. Cox regression models calculated the hazard ratio for dementia for each of the risk factors, after adjustment for age and sex.
Sci Rep
January 2025
School of Crop Production Technology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, Thailand.
Several mungbean (Vigna radiata (L.) Wilczek) cultivars are susceptible to Cercospora leaf spot (CLS) caused by Cercospora canescens Ellis & Martin, and it is necessary to explore resistance sources and understand resistance mechanisms. However, the CLS resistance mechanisms have not yet been explored.
View Article and Find Full Text PDFSci Rep
January 2025
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, 210094, China.
Background: Environmental metal exposure has been implicated in the development of digestive tract cancers, although the specific associations remain poorly defined. This study aimed to investigate the relationship between blood metal levels and the risk of digestive tract cancers among U.S.
View Article and Find Full Text PDFNat Commun
January 2025
Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
ATR plays key roles in cellular responses to DNA damage and replication stress, a pervasive feature of cancer cells. ATR inhibitors (ATRi) are in clinical development for treating various cancers, including those with high replication stress, such as is elicited by ARID1A deficiency, but the cellular mechanisms that determine ATRi efficacy in such backgrounds are unclear. Here, we have conducted unbiased genome-scale CRISPR screens in ARID1A-deficient and proficient cells treated with ATRi.
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