The atomically smooth surface of cleaved K(+)-mica is a common substrate for investigations of various phenomena at the mineral-water interface. In this study, K(+) inner-sphere adsorption above tetrahedral substitutions in the mica structure is found to be more favorable than that in mica's ditrigonal cavities for both dehydrated and hydrated cleaved mica. The activation energy necessary to transfer K(+) from the inner-sphere adsorption state to the outer-sphere adsorption state, in which K(+) can presumably migrate parallel to the surface, is calculated to be 45-48 kJ/mol on hydrated cleaved mica. The K(+) desorption state is predicted to be >13 A above the mica surface.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/la1026174 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evolution of anti-MICA antibodies after imlifidase infusion for a high immunological risk kidney transplantation.
Hum Immunol
January 2025
Service de Néphrologie, Dialyse et Transplantation, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; Laboratoire d'ImmunoRhumatologie Moléculaire, Institut national de la santé et de la recherche médicale (INSERM) UMR_S1109, Faculté de Médecine, Fédération Hospitalo-Universitaire OMICARE, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg, France; Laboratoire d'Excellence (LabEx) TRANSPLANTEX, Faculté de Médecine, Université de Strasbourg, Strasbourg, France; Institut Thématique Interdisciplinaire (ITI) de Médecine de Précision de Strasbourg, Strasbourg, France. Electronic address:
Imlifidase is an endopeptidase known for cleaving anti-Human Leucocyte Antigen donor-specific antibodies (DSA) to allow high-risk kidney transplantation. However, it lacks comprehensive data regarding its effect on alloantibodies targeting other histocompatibility antigens, such as Major Histocompatibility Complex class I chain-related protein A (MICA). This study describes the dynamics of anti-MICA antibodies following imlifidase administration in a kidney transplant recipient with anti-MICA*002 preformed DSA.
View Article and Find Full Text PDFMechanical Properties of Eye Lens Cortical and Nuclear Membranes and the Whole Lens.
Invest Ophthalmol Vis Sci
January 2025
Department of Physics, Boise State University, Boise, Idaho, United States.
Purpose: To elucidate the mechanical properties of the bovine lens cortical membrane (CM), the nuclear membrane (NM) containing cholesterol bilayer domains (CBDs), and whole bovine lenses.
Methods: The total lipids (lipids plus cholesterol) from the cortex and nucleus of a single bovine lens were isolated using the monophasic methanol extraction method. Supported CMs and NMs were prepared from total lipids extracted from the cortex and nucleus, respectively, using a rapid solvent exchange method and probe-tip sonication, followed by the fusion of unilamellar vesicles on a flat, freshly cleaved mica surface.
Concurrent (STK11, KL) mutant Non-Small Cell Lung Cancers (NSCLC) is particularly difficult to treat and does not respond well to current immune checkpoint blockade (ICB) therapies. This is due to numerous mechanisms including low antigen presentation limiting T cell mediated killing. To activate anti-tumor immunity, we targeted tumor cell - natural killer (NK) cell interactions.
View Article and Find Full Text PDFOncolytic adenovirus coding for shedding-resistant MICA enhances immune responses against tumors.
Cancer Immunol Immunother
January 2024
Cancer Immunotherapy Group, Oncobell and iProCURE programs, IDIBELL-Institut Català d'Oncologia, l'Hospitalet de Llobregat, Barcelona, Spain.
Cancer immunotherapies strive to overcome tumor-induced immune suppression and activate antitumor immune responses. Although cytotoxic T lymphocytes (CTLs) play a pivotal role in this process, natural killer (NK) cells have also demonstrated remarkable tumor-killing abilities, given their ability to discriminate tumor cells from normal cells and mediate specific antitumoral cytotoxicity. NK cells activation depends on a balance between activation and inhibition signals from several ligands/receptors.
View Article and Find Full Text PDFInteraction of β- and γ-Crystallin with Phospholipid Membrane Using Atomic Force Microscopy.
Int J Mol Sci
October 2023
Department of Physics, Boise State University, Boise, ID 83725, USA.
Highly concentrated lens proteins, mostly β- and γ-crystallin, are responsible for maintaining the structure and refractivity of the eye lens. However, with aging and cataract formation, β- and γ-crystallin are associated with the lens membrane or other lens proteins forming high-molecular-weight proteins, which further associate with the lens membrane, leading to light scattering and cataract development. The mechanism by which β- and γ-crystallin are associated with the lens membrane is unknown.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!