AI Article Synopsis
- Ingavirin effectively inhibits various strains of the influenza virus, including multiple H1N1, H5N1, and H3N2 variants.
- The drug demonstrates a reduction in hemagglutinin and cytopathic effects in MDCK cell cultures when introduced.
- These findings suggest potential therapeutic benefits of Ingavirin against influenza virus infections.
Article Abstract
Ingavirin was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v, as well as the strains A/Chicken/Kurgan/05/2005 (H5N1) and A/Aichi/2/68 (H3N2) in the MDCK cell culture. The hemagglutinin and cytopathic activity of the influenza virus strains decreased at entering Ingavirin in vitro.
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