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Country economic status is strongly associated with burn survival - validation of the (modified) ABSI.
Int J Equity Health
January 2025
Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Background: Predicting burn-related mortality is vital for family counseling, triage, and resource allocation. Several of the burn-specific mortality prediction scores have been developed, including the Abbreviated Burn Severity Index (ABSI) in 1982. However, these scores are not tested for accuracy to support contemporary estimates of the global burden of burn injury.
View Article and Find Full Text PDFMultidisciplinary integration and fusion based on critical care medicine and immunology: History, current status, and prospects.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2024
Third Xiangya Hospital, Central South University, Changsha 410013.
Critical care medicine focuses on understanding the pathophysiological mechanisms and treatment approaches for life-threatening conditions, including sepsis, severe trauma/burns, hemorrhagic shock, heatstroke, and acute pancreatitis, all of which have high incidence rates. These conditions are primarily characterized by acute multi-organ dysfunction, with sudden onset, severe illness, and high mortality rates. Additionally, critical care treatment demands substantial medical resources, imposing significant economic burdens on patients' families and society.
View Article and Find Full Text PDFIncreased prehospital mortality in patients with combined burns and trauma in Canada: Analysis of a provincial trauma registry database.
Burns
December 2024
Trauma Nova Scotia, Nova Scotia Health, Halifax, NS B3H 2Y9, Canada. Electronic address:
Introduction: The combination of burns and non-thermal trauma may have a synergistic effect on mortality. Our objective was to determine if burn patients with concomitant trauma are at increased risk of mortality in both the prehospital and in-hospital settings.
Methods: Data were collected from a population-based provincial trauma registry (2001-2019).
Association between urinary phthalate metabolites and sarcopenia in US adults from NHANES 2011-2018.
J Clin Endocrinol Metab
January 2025
Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital; Chongqing Key Laboratory of Precision Neuromedicine and Neuroregenaration, Third Military Medical University (Army Medical University), 400038 Chongqing, China.
Background: Phthalates, widely used as chemical additives, are often found as mixtures in the environment. However, the combined impact of phthalate exposure on sarcopenia remains unclear.
Objective: This study aimed to investigate the relationships between phthalates and sarcopenia in adults.
Recombinant Thrombomodulin Domain 1 Modulates Macrophage Polarization and Enhances Healing in Corneal Alkali Burns.
Invest Ophthalmol Vis Sci
January 2025
Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Purpose: Corneal alkali burns are severe ocular injuries characterized by intense inflammation, tissue damage, and vision impairment, with current treatments often insufficient in restoring corneal function and clarity. This study aimed to evaluate the therapeutic effects of recombinant thrombomodulin domain 1 (rTMD1) in the treatment of corneal alkali burns, focusing on its impact on inflammation, tissue repair, fibrosis, and neovascularization.
Methods: A murine model of corneal alkali burn was utilized to investigate the therapeutic potential of rTMD1.
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