AI Article Synopsis
- A study was conducted at a children's hospital in Buenos Aires from 2001 to 2003 to investigate yeast infections (fungaemia) in patients.
- The aim was to identify the types of yeast present and test their resistance to antifungal treatments.
- Results indicated that the most common species were Candida parapsilosis, Candida albicans, and Candida tropicalis, while some isolates showed tolerance to amphotericin B, suggesting potential treatment challenges.
Article Abstract
Background: A retrospective study on the epidemiology of fungaemia due to yeasts of medical importance at the Hospital Nacional de Pediatría Prof. Dr. J. Garrahan, Buenos Aires was conducted between September 2001 and September 2003.
Objectives: To learn the distribution of yeast species and to evaluate their in vitro antifungal susceptibility profile.
Methods: The minimum inhibitory concentration (MIC) was determined according to the CLSI M27-A2 procedure, and time kill curves against amphotericin B were also performed.
Results-conclusions: The species isolated were Candida parapsilosis (32.6% of isolates); Candida albicans (26.5%), Candida tropicalis (24.5%), and other yeasts (16.4%). Candida isolates were susceptible to the antifungals evaluated, but amphotericin B-tolerant isolates were detected using time kill curves.
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| http://dx.doi.org/10.1016/j.riam.2010.07.002 | DOI Listing |
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