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Transgenerational Plasticity of Maternal Hemolymph Trehalose in Aphids.
Arch Insect Biochem Physiol
January 2025
College of Agriculture, Ibaraki University, Inashiki, Japan.
Aphids exhibit a unique reproductive strategy known as pseudoplacental viviparity, in which embryos develop internally and are thought to receive nutrients such as sugars and amino acids directly from the maternal hemolymph through an ovariole sheath, bypassing the need for traditional yolk storage. This system enables viviparous aphids to adapt to diverse and potentially stressful environments by transmitting maternal environmental cues that influence transgenerational plasticity. However, the mechanisms underlying this nutrient-mediated plasticity are poorly understood.
View Article and Find Full Text PDFThe Expression of Proteases and the Oligopeptide Transporter in the Yolk Sac Membrane, Proventriculus, and Small Intestine During the Development of Embryo.
Biology (Basel)
November 2024
Department of Biology and Biotechnology, Faculty of Science, Hashemite University, P.O. Box 330127, Zarqa 13133, Jordan.
The role of the yolk sac membrane (YSM) and digestive tract in the processing of egg yolk proteins during embryogenesis is unexplored in the duck . Here, we investigated in the duck embryo the function of the YSM, proventriculus, and small intestine in protein digestion and uptake. We tested the expression of aminopeptidase N () and the oligopeptide transporter as well as the expression of cathepsin B () and cathepsin D () lysosomal genes in the YSM during incubation days 12, 14, 16-18, 20, 22, 24, 26, and 28 (the day of hatch).
View Article and Find Full Text PDFA rare case of huge intracranial yolk sac tumor presenting as an orbital mass in an infant: case report and literature review.
Discov Oncol
December 2024
Department of Radiology, Addis Ababa University, Addis Ababa, Ethiopia.
Primary intracranial yolk sac tumor (YST) with orbital involvement is an exceedingly rare extragonadal germ cell tumor, with only a limited number of cases reported in the literature. Clinically, primary intracranial yolk sac tumor with orbital involvement may present with symptoms that mimic more common benign or malignant orbital disorders in children, potentially leading to diagnostic delays that can adversely impact survival. Diagnostic imaging modalities, including computed tomography (CT) and magnetic resonance imaging (MRI), are instrumental for assessing the tumor's size, precise localization, and extent.
View Article and Find Full Text PDF[Primary uterine hepatoid adenocarcinoma: Clinicopathological analysis of 2 cases and literature review].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Pathology, Fujian Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.
Primary hepatoid adenocarcinoma (HAC) of the uterus is a particular tumour that bears high similarity to hepatocellular carcinoma histologically, and may easily be misdiagnosed because it is rare if you don' t remember it. In this report, we describe two cases of alpha-fetoprotein (AFP)-producing HAC of the uterus. Case 1 was a 69-year-old postmenopausal woman who was presented to the hospital for a medical examination.
View Article and Find Full Text PDFImmunomodulatory Effects of Modified Colostrum, Whey, and Their Combination With Other Natural Products: Effects on Natural Killer Cells.
Curr Ther Res Clin Exp
June 2024
Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Objectives: Natural killer (NK) cells are important immune system effector cells providing innate defenses against intracellular infections, including viral infections, immune surveillance, and cancer immunoediting. The primary purpose of this study was to investigate whether modified ultra-filtrated colostrum (UC) and hydrolyzed whey (W) products or their combinations with other natural products with reported immunomodulatory properties will stimulate NK cell cytotoxic activity by activation of granzyme B and IFN-γ production.
Methods: The ability of study products to stimulate the cytotoxic activity of human-purified CD56 NK cells and the production of granzyme B and IFN-γ by activated NK cells was evaluated in the cytotoxic assay.
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