A Q-switched Tm:fiber-laser-pumped Ho:LuLiF(4) laser is reported that has been optimized for high-energy pulses at low repetition rates. Operating at 100Hz, a pulse energy of 24.8mJ with pulse widths of 47ns at a wavelength of 2052nm was achieved. The beam propagation factor (M(2)) was measured to be approximately 1.04 at the maximum pump power, confirming fundamental transverse mode (TEM(00)) operation. Starting the pump laser at maximum power, the pulse energies of each of the first 10 pulses are >47mJ. This strong influence of crystal temperature on laser performance is discussed with the prospect for further improvement of the laser efficiency.
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http://dx.doi.org/10.1364/OL.35.002609 | DOI Listing |
Cell Div
January 2025
Babak Myeloma Group, Department of Pathophysiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Background: Multiple myeloma (MM) represents the second most common hematological malignancy characterized by the infiltration of the bone marrow by plasma cells that produce monoclonal immunoglobulin. While the quality and length of life of MM patients have significantly increased, MM remains a hard-to-treat disease; almost all patients relapse. As MM is highly heterogenous, patients relapse at different times.
View Article and Find Full Text PDFJ Nanobiotechnology
January 2025
School of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, China.
With the progress of atherosclerosis (AS), the arterial lumen stenosis and compact plaque structure, the thickening intima and the narrow gaps between endothelial cells significantly limit the penetration efficiency of nanoprobe to plaque, weakening the imaging sensitivity and therapy efficiency. Thus, in this study, a HO-NIR dual-mode nanomotor, Gd-doped mesoporous carbon nanoparticles/Pt with rapamycin (RAPA) loading and AntiCD36 modification (Gd-MCNs/Pt-RAPA-AC) was constructed. The asymmetric deposition of Pt on Gd-MCNs catalyzed HO at the inflammatory site to produce O, which could promote the self-motion of the nanomotor and ease inflammation microenvironment of AS plaque.
View Article and Find Full Text PDFJ Expo Sci Environ Epidemiol
January 2025
Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Background: Elemental analysis of teeth allows for exposure assessment during critical windows of development and is increasingly used to link early life exposures and health. The measurement of inorganic elements in teeth is challenging; laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is the most widely used technique.
Objective: Both synchrotron x-ray fluorescence (SXRF) and LA-ICP-MS have the capability to measure elemental distributions in teeth with each having distinct advantages and disadvantages.
Int Ophthalmol
January 2025
Department of Ophthalmology, Peking University Third Hospital, No 49 Huayuan North Road, Haidian District, Beijing, 100191, China.
Purpose: To evaluate clinical outcomes and visual quality 12 months after small incision lenticule extraction (SMILE) for correction of myopia with or without astigmatism in patients during the incipient phase of presbyopia.
Setting: Peking University Third Hospital, Beijing, China.
Design: Retrospective observation study.
Nature
January 2025
Department of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.
A particle current generated by pumping in the absence of gradients in potential energy, density or temperature is associated with non-trivial dynamics. A representative example is charge pumping that is associated with the quantum Hall effect and the quantum anomalous Hall effect. Spin pumping, the spin equivalent of charge pumping, refers to the emission of a spin current by magnetization dynamics.
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