[Concentration of plasma fibronectin and metabolism indices in the bone tissue of healthy children and in children with rickets].

A study was made of the content of plasma fibronectin as compared to the biochemical parameters of mineral and collagen metabolism in 177 children. Of these, there were 90 healthy children aged 1 month to 2 years and 87 children of the same age with grade I and II rickets at the height of illness. A close interrelation was established of the metabolic parameters characterizing metabolism of osseous tissue both in healthy children and in those with rickets. In the latter ones, plasma fibronectin was discovered to significantly decrease as the process becomes graver and more active. Besides, its level was found to be related to collagen metabolism.