A 14-year-old boy presented with fevers and nonspecific flu-like symptoms, as well as an enlarging ulcerated plaque involving the upper back, lymphadenopathy, and bilateral pulmonary nodules. Bacterial cultures of ulcer tissue grew Francisella tularensis on enriched chocolate agar plates. Making the diagnosis requires a high index of suspicion, and communication with the laboratory to successfully and safely culture these highly pathogenic bacteria is imperative.
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Tularemia in Pediatric Patients: A Case Series and Review of the Literature.
Pediatr Infect Dis J
September 2024
Laboratoire de Microbiologie, Hôpital Robert Debré, AP-HP, Paris, France.
Article Synopsis
- Tularemia is often misdiagnosed in children due to its similar symptoms to other common lymphadenopathy diseases, leading to delayed treatment; awareness among pediatricians is crucial.
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- Effective treatment typically includes aminoglycosides, fluoroquinolones, or tetracyclines, and pediatricians should consider tularemia in cases of febrile lymphadenopathy to avoid unnecessary costs from misguided antibiotic treatments and extended hospital stays.
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J Clin Ultrasound
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School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Erzincan University, Erzincan, Turkey.
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Oxf Med Case Reports
April 2024
Center for Infectious Diseases, Queen Astrid Military Hospital, Rue Bruyn 1, 1120, Brussels, Belgium.
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Background: Tularemia is an important reemerging disease with a multimodal transmission pattern. Treatment outcomes of current recommended antibiotic regimens (including ciprofloxacin and doxycycline) remain unclear. In this retrospective cohort study, we report clinical, laboratory, geographical, and treatment outcomes of laboratory-confirmed tularemia cases over an 11-year period in Northern Sweden.
View Article and Find Full Text PDFSeroepidemiology of Human Tularemia-Systematic Review and Meta-analysis of Seroprevalence Studies.
Open Forum Infect Dis
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Division of Pediatric Infectious Disease, Department of Pediatrics, Bern University Hospital, University of Bern, Bern, Switzerland.
Background: Seroepidemiologic studies of human tularemia have been conducted throughout the northern hemisphere. The purposes of this study were (1) to provide an overview of seroprevalence data, and (2) to generate an estimate of the proportion of study participants whose infection remained subclinical.
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