Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5.

Chem Commun (Camb)

School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Published: January 2011

hLDH-5 has emerged as a promising target for anti-glycolytic cancer chemotherapy. Here we report a first generation of bifunctional inhibitors, which show promising activity against hLDH-5.

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Source
http://dx.doi.org/10.1039/c0cc01166eDOI Listing

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