Diabetes is a major national health problem that affects African Americans more seriously than other population groups. The purpose of this project was to increase knowledge and self-management of diabetes among African American adults 40 years of age and older diagnosed with type II diabetes. A quasi-experimental pre-test/post-test comparison group design was used. Three educational sessions were provided to participants in the intervention group. Content included information about diabetes and its complications, risk factors, proper diet, recommendations for exercise, medications, and monitoring blood glucose. Teaching strategies included discussion, games, and demonstrations. Patient navigators provided follow-up by phone at the scheduled intervals. Preliminary results indicated significantly increased knowledge among intervention group participants between the pre- and post-test and the pre-test and follow-up. Findings for HbA1c values, body mass index, and weight were not significant.
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http://dx.doi.org/10.1353/hpu.0.0363 | DOI Listing |
JAMA Netw Open
January 2025
Department of Management, Policy, and Community Health, School of Public Health, The University of Texas Health Science Center, Houston.
Importance: COVID-19 vaccine hesitancy among Black women is a critical public health concern, potentially exacerbating existing health disparities and impacting community-wide vaccination efforts.
Objective: To explore the factors associated with COVID-19 vaccine hesitancy among Black women in the US and identify the specific concerns and experiences shaping hesitant attitudes toward vaccination.
Design, Setting, And Participants: Qualitative study using in-depth, semistructured interviews conducted virtually between June and November 2021.
J Racial Ethn Health Disparities
January 2025
Regenstrief Institute, Indianapolis, IN, USA.
African Americans (AAs) with end-stage kidney disease (ESKD) experience significant barriers to accessing living donor kidney transplantation (LDKT), largely due to individual and systemic factors, including a lack of trust in healthcare systems resulting from a legacy of and continued experiences with medical racism. This cross-sectional study analyzed survey data from 416 AA patients with ESKD undergoing transplant evaluation in 2019-2023 at two kidney transplant centers in the Southeast United States, examining whether trust (specifically trust in kidney doctors, hospitals, and healthcare) modifies the relationship between attitudes towards LDKT and behavioral intentions to discuss LDKT with family and friends. Multivariable analyses revealed significant interactions.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California, Los Angeles Integrative Biology and Physiology (IBP), Los Angeles, CA, USA.
Background: APOE is in linkage disequilibrium with the length of poly-T repeats at the rs10524523 ('523) locus of the TOMM40 gene. APOE-ε3 is associated with short (S) and (VL) variants of '523 in white and Black individuals. In white individuals, APOE-ε4 is associated with the long (L) '523 variant, but is associated with '523-S, '523-L, and '523-VL variants in Black individuals.
View Article and Find Full Text PDFBackground: Biomarkers, such as blood p-tau181, p-tau217, and p-tau231, have been created and verified to mirror the pathophysiology of tau and amyloid-β (Aβ) in the brain . Sleep spindles are known to contribute to memory consolidation and generalization and may therefore be a promising biomarker in preclinical Alzheimer's Disease (AD) . The present study investigated the relationship between sleep spindles and p-tau levels in cognitively healthy older African Americans.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Background: Type 2 diabetes mellitus (T2DM) is a risk factor for Alzheimer disease (AD) and disproportionately impacts under-represented groups including Mexican Americans/Hispanics (MAs) and African Americans/Blacks (AAs) compared to non-Hispanic Whites (NHWs). However, it remains unclear how amyloid, tau, and neurodegeneration (AT(N)) AD imaging biomarkers and cognitive functioning differ across diabetic stages including non-diabetes, pre-diabetes, and T2DM in a diverse community-based cohort.
Method: Data were obtained from the well-characterized Health and Aging Brain Study: Health Disparities (HABS-HD) cohort, including MAs (n=612), AAs (n=676), and NHWs (n=725) with clinical, amyloid and tau positron emission tomography (PET), and cortical thickness measures from magnetic resonance imaging (MRI) scans.
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