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A Mobile Health Intervention to Support Collaborative Decision-Making in Mental Health Care: Development and Usability.
JMIR Form Res
January 2025
Early Intervention in Psychosis Advisory Unit for South-East Norway, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Background: Shared decision-making between clinicians and service users is crucial in mental health care. One significant barrier to achieving this goal is the lack of user-centered services. Integrating digital tools into mental health services holds promise for addressing some of these challenges.
View Article and Find Full Text PDFExploring the Ethical Implications of ChatGPT in Medical Education: Privacy, Accuracy, and Professional Integrity in a Cross-Sectional Survey.
Cureus
December 2024
Medical Education, ABWA Medical College, Faisalabad, PAK.
Background: The inclusion of artificial intelligence in medical education, specifically through the use of ChatGPT (OpenAI, San Francisco, CA), has transformed learning and generated many ethical questions. This study aims to analyze the medical students' ethical concerns about using ChatGPT in medical education, focusing on privacy, accuracy, and professional integrity.
Methods: The study format was a cross-sectional survey distributed to 219 medical students at ABWA Medical College, Pakistan.
Solar-based technologies for removing potentially toxic metals from water sources: a review.
Environ Sci Pollut Res Int
January 2025
Departamento de Ciência E Tecnologia de Alimentos, Universidade Federal de Santa Catarina, Rod. Admar Gonzaga, 1346, Itacorubi, Florianópolis, Santa Catarina, 88034-001, Brazil.
Technological advances have led to a proportional increase in the deposition of contaminants across various environmental compartments, including water sources. Heavy metals, also known as potentially toxic metals, are of particular concern due to their significant harmful impacts on environmental and human health. Among the available methods for mitigating the threat of these metals in water, solar radiation-based technologies stand out for their cleanliness, cost-effectiveness, and efficiency in removing or reducing the toxicity of heavy metals.
View Article and Find Full Text PDFPopulation pharmacokinetics and exposure-response analysis of durvalumab in combination with gemcitabine and cisplatin in patients with advanced biliary tract cancer.
Cancer Chemother Pharmacol
January 2025
Clinical Pharmacology & Quantitative Pharmacology, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA, USA.
Purpose: Durvalumab in combination with gemcitabine/cisplatin has shown a favorable benefit-risk profile in the TOPAZ-1 study for advanced biliary tract cancers (BTC). This analysis evaluated the population pharmacokinetics (PopPK) of durvalumab, and exposure-response for efficacy and safety (ERES) of TOPAZ-1.
Methods: The PopPK model for durvalumab was updated using data from 5 previously analysed studies and TOPAZ-1.
The impact of demographics and positioning on the imaging features of the optic nerve sheath and ophthalmic vessels.
Ultrasound J
January 2025
Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.
Background: There are significant discrepancies in the optic nerve sheath diameter (ONSD) reported in the literature. We aimed to determine the ultrasonographic imaging features of ONSD and ophthalmic vessels in a healthy population, using a standardized protocol, and to estimate the effect of demographics and positioning changes on imaging measurements.
Methods: We measured the mean values of the ONSD in supine and sitting position and the Doppler imaging parameters of the ophthalmic, central retinal and short posterior ciliary arteries.
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