Adsorption and bioactivity of tyrosine hydroxylase on gold surfaces and nanoparticles.

Protein Pept Lett

Department of Biomedicine, University of Bergen, Jonas Lies vei 91, N-5009 Bergen, Norway.

Published: November 2010

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Article Abstract

Tyrosine hydroxylase is studied in terms of adsorption behaviour on gold surfaces and various passivating layers. Results reveal differences in layer formation, where mercaptoundecanoic acid-coated gold shows the best potential in terms of adsorbed mass. Nanoparticles with this coating are subsequently tested for enzymatic activity, which remains at attenuated levels.

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http://dx.doi.org/10.2174/0929866511009011376DOI Listing

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