An 8% strontium acetate, 1040 ppm sodium fluoride-based dentifrice has been demonstrated in in vitro and in situ studies to provide deep and acid-resistant tubule occlusion. Clinical efficacy studies have shown instant and lasting dentin hypersensitivity relief from this dentifrice, which has recently been launched by GlaxoSmithKline Consumer Healthcare as Sensodyne Rapid Relief.
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Strontium Carbonate and Strontium-Substituted Calcium Carbonate Nanoparticles Form Protective Deposits on Dentin Surface and Enhance Human Dental Pulp Stem Cells Mineralization.
J Funct Biomater
November 2022
Department of Chemistry, Ribeirão Preto Faculty of Philosophy, Sciences and Letters at Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-901, Brazil.
Strontium acetate is applied for dental hypersensitivity treatment; however, the use of strontium carbonates for this purpose has not been described. The use of Sr-carbonate nanoparticles takes advantage of both the benefits of strontium on dentin mineralization and the abrasive properties of carbonates. Here in, we aimed to synthesize strontium carbonate and strontium-substituted calcium carbonate nanoparticles and test them as potential compounds in active dentifrices for treating dental hypersensitivity.
View Article and Find Full Text PDFAntibacterial and Cytocompatible: Combining Silver Nitrate with Strontium Acetate Increases the Therapeutic Window.
Int J Mol Sci
July 2022
Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.
Microbial infection and insufficient tissue formation are considered to be the two main causes of dental implant failure. Novel studies have focused on designing dual-functional strategies to promote antibacterial properties and improve tissue cell response simultaneously. In this study, we investigated the antibacterial properties and cytocompatibility of silver nitrate (AgNO) and strontium acetate (SrAc) in a mono-culture setup for dental application.
View Article and Find Full Text PDFComparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial.
BMC Oral Health
October 2021
Department of Research, School of Public Health, Dow University of Health Sciences, Karachi, Pakistan.
Background: Dentin hypersensitivity (DH) is a sharp toothache that influences a patients' oral health-related quality of life. Oral dentifrices have been marketed for pain relief within a minute for DH. The permanent management of DH is being investigated with the remineralisation potential of bioactive agents in dentinal tubules.
View Article and Find Full Text PDFCombination of two desensitizing protocols to control dentin hypersensitivity in non-carious lesions: a randomized, double-blind clinical trial.
Clin Oral Investig
February 2022
Dental Materials Laboratory of the Postgraduate Program in Dentistry, Federal University of Pará, Belém, Pará, Brazil.
Objectives: This study evaluated the effect of photobiomodulation (PBM) combined with 8% strontium acetate (SA8%) in the treatment of dentin hypersensitivity (DH) in non-carious lesions and analyzed the risk factors with the patient's quality of life.
Methods: Eighty teeth with DH were randomly allocated into four treatment groups (n = 20): G1, PBM imitation + toothpaste with no active ingredient; G2, PBM imitation + toothpaste with SA8%; G3, PBM + toothpaste without the active ingredient; and G4, PBM + toothpaste with SA8%. Participants were provided with a questionnaire on the experience of dentin hypersensitivity (QEDH) to assess the impact of desensitizing treatment on health-related quality of life (HRQL).
Evaluating the antibacterial effect of synthesized herbal toothpastes and their efficacy for dentine tubule occlusion: Scanning electron microscopy and energy-dispersive X-ray spectroscopy analysis.
Microsc Res Tech
January 2022
Department of Microbiology and Virology, Kerman University of Medical Sciences, Kerman, Iran.
Article Synopsis
- The study evaluated the effectiveness of two herbal toothpastes made with pomegranate peel, Equisetum arvense extracts, and strontium acetate in occluding dentin tubules.
- Both toothpastes significantly reduced the number of open dentin tubules compared to a control group, with statistical validation.
- Scanning electron microscopy and energy-dispersive X-ray spectroscopy confirmed the occlusion and identified strontium and silica deposits on dentin tubules from the toothpaste containing Equisetum arvense.
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