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The overlap of diabetic and inflammatory neuropathies: Epidemiology, possible mechanisms, and treatment implications.
Clin Neurol Neurosurg
January 2025
Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Diabetic polyneuropathy is the common neuropathy of diabetes. However, several inflammatory neuropathies may occur during diabetes. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) represents the most treatable example.
View Article and Find Full Text PDFMultidisciplinary management of early esophageal fistula after anterior cervical spine surgery: a case report emphasizing team-based care.
Wound Manag Prev
December 2024
The First Affiliated Hospital, Unit of Nurses, Zhejiang University School of Medicine, Hangzhou, China.
Background: Early esophageal fistula formation following anterior cervical spine surgery presents a formidable clinical challenge, necessitating astute rehabilitative nursing management. Such fistulas, if not promptly and effectively managed, can precipitate grave complications including mediastinitis, sepsis, respiratory failure, and, in severe instances, mortality. This underscores the critical need for immediate, comprehensive nursing interventions designed to mitigate these risks and enhance patient outcomes.
View Article and Find Full Text PDFDifferential impact of lymphatic outflow pathways on cerebrospinal fluid homeostasis.
J Exp Med
February 2025
Brain Immunology and Glia (BIG) Center, Washington University in St. Louis, St. Louis, MO, USA.
Dysfunctional lymphatic drainage from the central nervous system (CNS) has been linked to neuroinflammatory and neurodegenerative disorders, but our understanding of the lymphatic contribution to CNS fluid autoregulation remains limited. Here, we studied forces that drive the outflow of the cerebrospinal fluid (CSF) into the deep and superficial cervical lymph nodes (dcLN and scLN) and tested how the blockade of lymphatic networks affects CNS fluid homeostasis. Outflow to the dcLN occurred spontaneously in the absence of lymphatic pumping and was coupled to intracranial pressure (ICP), whereas scLN drainage was driven by pumping.
View Article and Find Full Text PDFSelective otolithic dysfunction in patients presenting with acute spontaneous vertigo: consideration based on MRI.
Front Neurol
December 2024
Dizziness Center, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Objective: Acute unilateral peripheral vestibulopathy or vestibular neuritis (AUPV/VN) manifests as acute onset vertigo, often accompanied by nausea, vomiting, and moderate gait instability. It is suspected when vestibular hypofunction is documented on video-head impulse (video-HITs) and caloric tests in the presence of contralesionally beating horizontal-torsional nystagmus. Herein, we report patients presenting with acute vestibular syndrome (AVS) showing selective otolithic dysfunction in the presence of normal caloric and video-HITs and abnormal enhancement of the peripheral vestibular structures on MRI.
View Article and Find Full Text PDFObjective: To assess if patients with enlarged vestibular aqueduct (EVA) experience symptoms characteristic of other third mobile window disorders such as superior semicircular canal dehiscence syndrome (SCDS).
Study Design: Cross-sectional study.
Setting: Tertiary care center.
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