Questions have risen regarding procedural indications, techniques, and outcomes for hybrid arch procedures. We performed a meta-analysis to benchmark this innovative approach. Studies and case reports involving hybrid aortic arch procedures listed through May 2008 were reviewed (n = 718). End points were 30-day mortality, stroke, paraplegia, and endoleak rates. A total of 15 studies with 463 patients were included in the meta-analysis. Overall 30-day mortality was 8.3%. Endoleak rate was 9.2%, stroke was 4.4%, and paraplegia was 3.9%. Treated on-pump or off-pump did not affect any of the endpoints. Results compare favorably with standard operative repair. Long-term follow-up is needed.
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http://dx.doi.org/10.1016/j.athoracsur.2009.12.016 | DOI Listing |
J Vasc Surg
December 2024
Division of Vascular and Endovascular Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
Objectives: Patients that survive acute aortic dissection (AD) remain at high risk of morbidity/mortality from structural changes of the aorta. Aortic surveillance is challenging, especially within a tertiary referral center. Our aim was to identify follow-up imaging and appointment rates, and factors associated with incomplete surveillance in patients with acute AD.
View Article and Find Full Text PDFGeorgian Med News
October 2024
1Jo Ann University Hospital, Tbilisi, Georgia.
Collateral vascular arteries from the descending aorta to the pulmonary arteries are uncommon after arterial switch operation. We describe a case of transposition of the great arteries (TGA) with significant aortopulmonary collateral vessels causing management difficulties after an arterial switch operation. Preoperatively, the presence of collaterals exacerbated aortic diastolic runoff and led to myocardial ischemia.
View Article and Find Full Text PDFJ Atheroscler Thromb
December 2024
Department of Neurology, Juntendo University Urayasu Hospital.
Aims: Atherogenic dyslipidemia (AD) is regarded as a residual risk of cardiovascular diseases characterized by low high-density lipoprotein cholesterol (HDL-C) and high triglyceride (TG) levels and related to the intracranial stenosis of atheromatous thrombotic brain infarction (ATBI). Further, atherosclerosis is possibly related to another stroke subtype, including cryptogenic stroke (CS). In particular, an aortic complicated lesion (ACL) is a notable embolic source of CS, since recurrence of aortogenic brain embolism is not rare.
View Article and Find Full Text PDFRegen Ther
March 2025
Department of Neurorehabilitation, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China.
Spinal cord ischemia/reperfusion (IR) injury (SCII) can cause major autonomic, sensory, and motor damage and loss. The upregulation of Nrf2, a primary orchestrator of the oxidative stress response, has beneficial effects in SCII. Here, we aimed to uncover a SCII-related transcription factor that is able to elevate Nrf2 expression.
View Article and Find Full Text PDFTransfusion
December 2024
Cerus Corporation, Concord, California, USA.
Background: The clinical significance of natural and treatment-emergent antibodies specific for amustaline/glutathione pathogen-reduced red blood cells (PRRBCs) is not known.
Study Design And Methods: A Phase 3, randomized clinical trial of PRRBCs (ReCePI) compared PRRBCs with conventional RBCs in cardiac or thoracic-aorta surgery. Subjects transfused during and for 7 days after surgery were screened for PRRBC-specific antibodies at baseline, 28 and 75 days post-surgery.
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