The interest in low-cost microfluidic platforms as well as emerging microfabrication techniques has increased considerably over the last years. Toner- and paper-based techniques have appeared as two of the most promising platforms for the production of disposable devices for on-chip applications. This review focuses on recent advances in the fabrication techniques and in the analytical/bioanalytical applications of toner and paper-based devices. The discussion is divided in two parts dealing with (i) toner and (ii) paper devices. Examples of miniaturized devices fabricated by using direct-printing or toner transfer masking in polyester-toner, glass, PDMS as well as conductive platforms as recordable compact disks and printed circuit board are presented. The construction and the use of paper-based devices for off-site diagnosis and bioassays are also described to cover this emerging platform for low-cost diagnostics.
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http://dx.doi.org/10.1002/elps.201000063 | DOI Listing |
Front Digit Health
June 2024
Department of Technology Transfer Office, Alanya University, Antalya, Türkiye.
Sci Rep
August 2023
School of Materials Science and Engineering, Lanzhou Jiaotong University, Lanzhou, 730070, China.
Laserjet printing is a kind of facile and digital do-it-yourself strategies, which is of importance to fabricate inexpensive paper-based microfluidic devices. However, the printed hydrophobic barrier is not hydrophobic enough due to the weak hydrophobicity and requires subsequent heating, which can lead to the pyrolysis of cellulose in the paper and influence the detection results. Here, for the first time, we report a kind of functional toner including toner and polydopamine (PDA) nanocapsules which contains oleic acid modified ferric tetroxide (OA-FeO) and octadecylamine (ODA), which is suitable for printing with desired shapes and sizes to lead to formation of superhydrophobic barriers.
View Article and Find Full Text PDFPolymers (Basel)
February 2022
Department of Chemical Engineering, National Cheng Kung University, No. 1 University Road, Tainan 70101, Taiwan.
Since the monumental work conducted by Whitesides et al. in 2007, research and development of paper-based microfluidics has been widely carried out, with its applications ranging from chemical and biological detection and analysis, to environmental monitoring and food-safety inspection. Paper-based microfluidics possesses several competitive advantages over other substrate materials, such as being simple, inexpensive, power-free for fluid transport, lightweight, biodegradable, biocompatible, good for colorimetric tests, flammable for easy disposal of used paper-based diagnostic devices by incineration, and being chemically modifiable.
View Article and Find Full Text PDFRSC Adv
August 2020
Pillar of Engineering Product Development, Singapore University of Technology and Design 8 Somapah Road Singapore 487372 Singapore +65 6499 4867.
This paper describes a method to fabricate microfluidic paper-based analytical devices (μPADs) using a toner laser printer. Multiple methods have been reported for the fabrication of μPADs for point-of-care diagnostics and environmental monitoring. Despite successful demonstrations, however, existing fabrication methods depend on particular printers, in-house instruments, and synthetic materials.
View Article and Find Full Text PDFCurr Top Microbiol Immunol
December 2019
Johns Hopkins Center for Health Security, 621 E. Pratt Street Suite 201, Baltimore, MD, 21202, USA.
Predicting which pathogen will confer the highest global catastrophic biological risk (GCBR) of a pandemic is a difficult task. Many approaches are retrospective and premised on prior pandemics; however, such an approach may fail to appreciate novel threats that do not have exact historical precedent. In this paper, based on a study and project we undertook, a new paradigm for pandemic preparedness is presented.
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