There are several atlases available showing prenatal human development. However, none is focused on prenatal orofacial development during maxillary and mandibular bone formation. These events, together with dental development and formation of the temporomandibular joint, take place during several fetal stages. While photographic atlases are limited to depicting the outer shape, and atlases based on histological sections only show a series of single sections, an atlas based on three-dimensional reconstructions from serial sections can show both the outer skin and the structures underneath, which can be electronically dissected layer by layer. In this Focus article, we present our atlas on prenatal human orofacial development, which is accessible online at the Journal's website.
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http://dx.doi.org/10.1111/j.1600-0722.2010.00756.x | DOI Listing |
J Hazard Mater
December 2024
College of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China; Research Unit Analytical BioGeoChemistry, Helmholtz Munich, Neuherberg 85764, Germany; Xiamen Key Laboratory of Marine Functional Food, Xiamen 361021, China. Electronic address:
Bisphenol S (BPS) is widely used as a substitute for Bisphenol A (BPA). While perinatal BPS exposure is suspected to increase susceptibility to high-caloric diet-induced adipogenesis, how BPS affects offspring remains largely unknown. This study explored effects of prenatal BPS exposure on adiposity and insulin resistance in high-fat diet (HFD)-fed C57BL/6 offspring, revealing significant changes in body weight, glucose tolerance, insulin sensitivity, and histopathology.
View Article and Find Full Text PDFImmunol Cell Biol
November 2024
Department of Immunology, School of Translational Medicine, Monash University, Melbourne, VIC, Australia.
Eur J Epidemiol
November 2024
Department of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
The China Prospective Multi-Center Birth Cohort Study was launched in 2022. In collaboration with medical centers in 12 cities, it aims to establish a high-quality, multidimensional cohort comprising 20,000 natural pregnancy and assisted reproductive families. As of June 26, 2024, 12,911 pregnant women have participated in this study, and 161,122 biological samples have been collected.
View Article and Find Full Text PDFNat Commun
November 2024
Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
The third trimester of human gestation is characterised by rapid increases in brain volume and cortical surface area. Recent studies have revealed a remarkable molecular diversity across the prenatal cortex but little is known about how this diversity translates into the differential rates of cortical expansion observed during gestation. We present a digital resource, μBrain, to facilitate knowledge translation between molecular and anatomical descriptions of the prenatal brain.
View Article and Find Full Text PDFNat Rev Immunol
October 2024
Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
The human immune system is made up of a huge variety of cell types each with unique functions. Local networks of resident immune cells are poised to sense and protect against pathogen entry, whereas more widespread innate and adaptive immune networks provide first rapid, then long-lasting and targeted responses. However, how we develop such a diverse and complex system remains unknown.
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