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Preparative Isolation of N-glycans from Natural Sources Mediated by a Deglycosylating Heterogeneous Biocatalyst in Flow.
ChemSusChem
January 2025
CIC biomaGUNE, Heterogeneous Biocatalysis, Paseo Miramon 182, 20009, San Sebastian, SPAIN.
EEfficient methods for isolating N-glycans are essential to understanding the functions and characteristics of the entire N-glycome. Enzymatic release using PNGaseF is the most effective approach for releasing mammalian N-glycans for analytical purposes. However, the use of PNGaseF for preparative N-glycan isolation is precluded due to the enzyme's cost and limited stability.
View Article and Find Full Text PDFCritical care services in Bagmati province of Nepal: A cross sectional survey.
Wellcome Open Res
December 2024
Nepal Health Research Council, Kathmandu, Bagmati Province, Nepal.
Background: This study aimed to assess the current status of critical care services in 13 districts of Bagmati Province in Nepal, with a focus on access, infrastructure, human resources, and intensive care unit (ICU) services.
Methods: A cross-sectional survey was conducted among healthcare workers employed in 87 hospitals having medical/surgical ICUs across Bagmati Province. Data were collected through structured questionnaires administered via face-to-face and telephone interviews.
Effect of Fast-Track Surgery Based on Nutritional Support in the Rehabilitation of Patients Undergoing Radical Thyroidectomy and Lateral Lymphadenectomy: A Retrospective Analysis.
Ann Ital Chir
January 2025
Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan, Hubei, China.
Aim: This study aims to investigate the impact of fast-track surgery (FTS), based on nutritional support, on postoperative rehabilitation and nutritional status in patients undergoing radical thyroidectomy and lateral lymphadenectomy.
Methods: This retrospective study included 112 patients who underwent radical thyroid cancer surgery and lateral neck lymph node dissection at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, between April 2021 and April 2023. Based on various nursing methods, patients were divided into two groups, with 58 patients included in the observation group (FTS care based on nutritional support), and 54 patients in the control group (routine perioperative care).
Trends in psychiatric emergency visits: insights from France's largest psychiatric emergency department.
Int J Emerg Med
January 2025
Centre Psychiatrique d'Orientation Et d'Accueil (CPOA), GHU Paris Psychiatrie Et Neurosciences, Site Sainte-Anne, 1 Rue Cabanis, Paris, 75014, France.
Introduction: Psychiatric emergency departments (EDs) in France have been under pressure from several factors, exacerbated by the COVID-19 pandemic. The pandemic led to an increase in psychiatric disorders, particularly anxiety and depression, with younger people and women being most affected. The aim of this study was to provide a comprehensive description of the trends in the number of visits to the largest psychiatric emergency department in France, with a particular focus on the period preceding and following the advent of COVID-19 pandemic.
View Article and Find Full Text PDFAn experimental test of eco-evolutionary dynamics on rocky shores.
Ecology
January 2025
Bodega Marine Laboratory, University of California Davis, Bodega Bay, California, USA.
A growing body of theoretical studies and laboratory experiments has focused attention on reciprocal feedbacks between ecological and evolutionary processes. However, uncertainty remains about whether such eco-evolutionary feedbacks have an important or negligible influence on natural communities. Thus, recent discussions call for field experiments that explore whether selection on phenotypic variation within populations leads to contemporaneous effects on community dynamics.
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