Diastereoisomers of diethyl 5-substituted (2-thioxo-imidazolidin-4-yl)phosphonates, which can be regarded as protected diethyl 1,2-diaminoalkylphosphonates, have been analyzed by electron ionization mass spectrometry. Significant differences in the fragmentation of cis- and trans-diastereoisomers were found. The stereospecificity of the elimination of diethyl phosphonate and the loss of the diethoxyphosphoryl group were studied using specific labeled compounds and collision-induced dissociation. The relative abundances of ions formed via these fragmentation processes can be used for differentiation of both diastereoisomers.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/rcm.4644 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diethyl nitrosamine-induces neurobehavioral deficit, oxido-nitrosative stress in rats' brain: a neuroprotective role of diphenyl diselenide.
BMC Neurosci
December 2024
Department of Anatomy, Faculty of Basic Medical Sciences, University of Ibadan, Ibadan, Oyo State, Nigeria.
Diethylnitrosamine (DEN), a common dietary carcinogen, is associated with neurotoxicity in humans and animals. This study investigated the neuroprotective effects of diphenyl diselenide (DPDS) against DEN-induced neurotoxicity in male Albino Wistar rats (n = 40). Rats were randomly distributed into cohorts and treated as follows: vehicle control (corn oil 2 mL/kg; gavage), DPDS-only (5 mg/kg; gavage) and DEN-only (200 mg/kg; single dose i.
View Article and Find Full Text PDFThe effect of synergists on the inhibition of detoxification enzyme activities and acaricide sensitivity in Rhizoglyphus robini.
Exp Appl Acarol
December 2024
Department of Plant Protection, Faculty of Agriculture, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran.
The saffron bulb mite, Rhizoglyphus robini Claparede (Acari: Acaridae), is the most important pest of the saffron crop in Iran. This pest attacks and feeds on saffron corms. For this reason, the corms are treated with acaricides before planting.
View Article and Find Full Text PDFIn vitro and in vivo studies of selenium nanoparticles coated bacterial polysaccharide as anti-lung cancer agents.
Microb Cell Fact
December 2024
Department of Botany and Microbiology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Microbial exopolysaccharides (EPSs) possess valuable biological functions and fascinating physicochemical properties. On the other hand, lung cancer is the primary contributor to global cancer-related deaths. However, health and safety concerns have prevented the identification and approval of any medications, including chemotherapeutic agents, for lung cancer treatment to date.
View Article and Find Full Text PDFBehenic acid protects the testosterone cycle and prevents the sperm apoptosis and protein loss in phthalate exposure by inhibiting oxidative stress and stimulating ATPase activity.
Toxicol Rep
December 2024
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, P.O. Box.11562, Cairo, Egypt.
Background: Plastic products use phthalate to enhance their flexibility, transparency, and stability, while behenic acid is a carboxylic acid with antioxidant activity.
Objectives: This study evaluates whether behenic acid can protect the testosterone cycle and prevent the sperm apoptosis and protein loss in phthalate-treated male rats.
Methods: There were 36 male albino rats in all, divided into six equal sets of six rats each: control, behenic acid (13 g/kg), behenic acid (26 g/kg), diethyl phthalate (10 mg/kg), behenic acid (13 g/kg) + diethyl phthalate (10 mg/kg), and behenic acid (26 g/kg) + diethyl phthalate (10 mg/kg)-treated groups.
Pesticide contamination and associated ecological risks in estuarine waters of Brazil's Legal Amazon.
Environ Sci Pollut Res Int
December 2024
Laboratório de Química Analítica E Ecotoxicologia (LAEC), Federal University of Maranhão (UFMA), Av. Dos Portugueses, 1966, São Luís, Maranhão, 65080-805, Brazil.
Pesticide contamination remains a significant environmental concern globally, with important implications for aquatic ecosystems. Despite being one of the world's largest pesticide consumers, monitoring and assessment of pesticide pollution are limited in Brazil, especially in sensitive regions like the Amazon. In this study, the occurrence and environmental risks of 8 pesticides of different classes, namely alachlor, atrazine, chlorfenvinphos, isoproturon, irgarol, simazine, diuron, and its transformation product DCPMU (1-(3,4-dichlorophenyl)-3-methyl urea) were analysed in surface water of the São Marcos Estuarine Complex (SMEC) in two consecutive years.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!