Purpose: Categorization of gastroschisis into low risk (simple) and high risk (complex) has been reported as an important determinant of outcome. The role of risk categorization in choosing the optimal surgical approach is unreported. This study aims to investigate the role of risk categorization in decision making for ward reduction of gastroschisis.
Methods: Data on a cohort of 52 consecutive neonates with gastroschisis between 2000 and 2009 were reviewed. A clinical pathway based on risk categorization was implemented in 2004, and children with simple gastroschisis underwent ward reduction and those with complex gastroschisis underwent surgical closure. Thirty-three neonates since 2004 were analysed and compared to the 19 born prior to 2004.
Results: Of the 33 children with gastroschisis in the study group, 23 were assessed as simple and underwent ward reduction with 96% survival. Ten had complex gastroschisis and underwent varying surgical procedures. Only six out of ten children (60%) with complex gastroschisis survived in spite of multiple surgical attempts.
Conclusions: Risk stratification of gastroschisis at birth helps in choosing optimal surgical management. Ward reduction can be successfully and safely performed in all children with simple gastroschisis. Those with complex gastroschisis require conventional surgical treatment.
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http://dx.doi.org/10.1007/s00383-010-2659-5 | DOI Listing |
BMJ Open Qual
December 2024
DIALOG Programme, Surrey and Borders Partnership NHS Foundation Trust, Leatherhead, UK.
Falls in the inpatient units are the most frequently reported patient safety incidents and their consequences can be devastating. Risk factors for falls are broadly categorised into two factors-'extrinsic and intrinsic' and while the effect of functional mental health conditions on falls has not been extensively studied, older adults with dementia are at a higher risk of falling. Their impact could lead to delayed functional recovery, distress, increased length of hospital stays and an increased fear of falling.
View Article and Find Full Text PDFFront Nutr
December 2024
Department of Clinical Laboratory, Dalian Women and Children's Medical Group, Dalian, China.
Background: The interaction between the human breast milk microbiota and human milk oligosaccharides (HMOs) plays a crucial role in the healthy growth and development of infants. We aimed to clarify the link between the breast milk microbiota and HMOs at two stages of lactation.
Methods: The microbiota and HMOs of 20 colostrum samples (C group, 1-5 days postpartum) and 20 mature milk samples (S group, 42 days postpartum) collected from postpartum mothers were analyzed using 16S rRNA gene high-throughput sequencing and high-performance liquid chromatography-tandem mass spectrometry.
Gastric Cancer
December 2024
Department of Gastrointestinal Surgery, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi Ward, Yokohama, Kanagawa, 241-8515, Japan.
Background: Identifying the most effective postoperative surveillance interval in patients with gastric cancer (GC) remains challenging. To elucidate a logical and effective surveillance schedule, we analyzed GC recurrence risk trends after gastrectomy using the hazard function.
Methods: We retrospectively reviewed the medical records of 2503 patients who underwent curative GC resection between 2000 and 2018.
J Affect Disord
December 2024
School of Health and Wellbeing, University of Glasgow, Glasgow, UK; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Whether depression and poor sleep interact or have statistically independent associations with brain structure and its change over time is not known. Within a subset of UK Biobank participants with neuroimaging and subjective and/or objective sleep data (n = 28,351), we examined associations between lifetime depression and sleep disruption and their interaction with structural neuroimaging measures, both cross-sectionally and longitudinally. Sleep variables were: self-reported insomnia and difficulty getting up; actigraphy-derived short sleep (<7 h); sustained inactivity bouts during daytime (SIBD); and sleep efficiency.
View Article and Find Full Text PDFEnviron Monit Assess
December 2024
Faculty of Information Technology, University of Engineering and Technology, Vietnam National University Hanoi, E3 Building, 144 Xuan Thuy Street, Dich Vong Hau Ward, Cau Giay District, Ha Noi, 100000, Vietnam.
PM pollution is a major global concern, especially in Vietnam, due to its harmful effects on health and the environment. Monitoring local PM levels is crucial for assessing air quality. However, Vietnam's state-of-the-art (SOTA) dataset with a 3 km resolution needs to be revised to depict spatial variation in smaller regions accurately.
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