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[Epilepsy and psychiatric disorders (epi-psy)].

Rev Prat

November 2024

Service de psychiatrie, université de Lorraine et service de neurologie, hôpital central de Nancy, Nancy, France.

EPILEPSY AND PSYCHIATRIC DISORDERS (EPI-PSY). Epilepsy is not only a brain pathology characterized by a lasting predisposition to generate seizures, it is also associated with cognitive, behavioral, psychological, and social disorders. The interaction between psychiatric pathologies and epilepsy is bidirectional and complex.

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Article Synopsis
  • Psychiatric comorbidities are frequent and impactful in people with epilepsy, often going unrecognized and untreated due to a lack of mental health specialists and insufficient training for neurologists.
  • This special issue aims to equip neurologists with practical resources to effectively manage these comorbidities through proper pharmacotherapy.
  • Key topics covered include various psychiatric problems associated with epilepsy, strategies for recognition and treatment, and the importance of tailored management for individuals with a history of psychiatric disorders.
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Individuals with epilepsy are at risk of developing preictal, ictal, postictal and interictal psychoses. Antipsychotic drugs (APDs) are the main class of drugs used to treat psychosis and schizophrenia. The efficacy and safety of APDs as a treatment for epileptic psychosis is not well understood.

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Endogenous pain modulation after sleep restriction in migraine: a blinded crossover study.

J Headache Pain

October 2024

Department of Neuromedicine and Movement Sciences, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, Trondheim, 7491, Norway.

Background: Patients with migraine are vulnerable to insufficient sleep, but the impact of sleep restriction is largely unknown. In addition, the importance of sleep may be different in patients with migraine who mostly have attack onsets during sleep, so called sleep-related migraine, compared to patients with non-sleep-related migraine. In this study we investigate the effect of sleep restriction on endogenous pain modulation in patients with migraine and healthy controls.

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