Deuterium exchange of a carboxy group was achieved by photochemical decarboxylation of free carboxylic acids in the presence of thiol and a small amount of D(2)O, and a deuterated product with excellent deuterium content was obtained; this reaction is a practical means of synthesizing regioselective deuterium-labelled compounds under mild reaction conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c0cc01464h | DOI Listing |
Publication Analysis
Top Keywords
deuterium exchange
8
free carboxylic
8
carboxylic acids
8
photochemical decarboxylation
8
mild deuterium
4
exchange reaction
4
reaction free
4
acids photochemical
4
decarboxylation deuterium
4
exchange carboxy
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!