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Hidden Encephalopathy: A Mysterious Case.
Cureus
February 2025
Internal Medicine, Unidade Local de Saúde de Gaia e Espinho, Vila Nova de Gaia, PRT.
Hepatic encephalopathy (HE) is a complex neurological disorder characterized by a wide range of neuropsychiatric abnormalities, from subtle cognitive deficits to deep coma. While cirrhosis is the most common underlying condition, HE can also occur in other conditions. The pathogenesis of HE is multifactorial, but a key factor is the liver's impaired capacity to detoxify substances absorbed from the gut, notably ammonia.
View Article and Find Full Text PDFStreptococcus pneumoniae-Related Infective Endocarditis Complicated by Development of Psoas and Epidural Abscesses.
Cureus
February 2025
Family Medicine, Louisiana State University Health Sciences Center at Ochsner University Hospital and Clinics, Lafayette, USA.
(), a gram-positive bacterium in the upper respiratory tract, can cause pneumonia, meningitis, and bloodstream infections. septicemia may lead to cardiac valve seeding, increasing the risk of epidural and psoas abscesses. Understanding its pathology is crucial for improving early detection and intervention.
View Article and Find Full Text PDFDelayed Neurological Sequelae of Carbon Monoxide Intoxication Initially Treated as Infectious Meningo Encephalitis.
Eur J Case Rep Intern Med
March 2025
Service de Médecine Interne, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Unlabelled: We report the case of a 75-year-old woman admitted to the emergency department for confusion, gait disturbances and mutism associated with an inflammatory syndrome occurring 3 weeks after acute carbon monoxide intoxication. The main hypothesis upon arrival was infectious meningoencephalitis, and the patient was put on acyclovir and antibiotics in meningeal doses. After a short stay in intensive care, the patient's condition did not improve, and the revaluation of her case history and imaging studies led to the diagnosis of post-interval syndrome secondary to carbon monoxide intoxication after a 3-week asymptomatic period.
View Article and Find Full Text PDFAn interpretable machine learning-assisted diagnostic model for Kawasaki disease in children.
Sci Rep
March 2025
National Clinical Research Center for Child Health, National Children's Regional Medical Center, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Kawasaki disease (KD) is a syndrome of acute systemic vasculitis commonly observed in children. Due to its unclear pathogenesis and the lack of specific diagnostic markers, it is prone to being confused with other diseases that exhibit similar symptoms, making early and accurate diagnosis challenging. This study aimed to develop an interpretable machine learning (ML) diagnostic model for KD.
View Article and Find Full Text PDFPeople with Adrenal Insufficiency who are in Adrenal Crisis are Frequently Unable to Self-Administer Rescue Injections.
Endocr Pract
March 2025
Division of Rheumatology, Department of Medicine, National Jewish Health, Denver CO. USA. Electronic address:
Objectives: Individuals with adrenal insufficiency (AI) are at risk of acute adrenal crisis and death, particularly during illness or trauma, and may require rapid treatment with parenteral glucocorticoid such as hydrocortisone (HC) to manage a crisis. Current guidelines recommend timely self-injection in an evolving crisis. Little is known about the patient experience with emergency injections.
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