Purpose: To evaluate intracorneal continuous ring (ICCR) implantation for the treatment of keratoconus.

Setting: Eye specialist centers, Europe and Middle East.

Method: This study assessed the results of implantation of a MyoRing ICCR in 15 eyes with keratoconus. Outcome measures included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA) (spectacle correction), refraction, complications, and side effects. Postoperative follow-up was up to 1 year.

Results: The study evaluated 15 eyes of 11 patients (8 men, 3 women) with a mean age of 35 years +/- 12 (SD) (range 22 to 60 years). Preoperatively, the mean central corneal thickness was 435 +/- 41 mum (range from 350 to 485 mum) and the mean keratometry (K) readings, 48.96 +/- 3.4 diopters (D) (range 43.75 to 56.62 D). Postoperatively, there was a statistically significant improvement in the UDVA, CDVA, K readings, manifest spherical and cylindrical refractive errors, and spherical equivalent (P<.05). The mean UDVA improved by almost 10 lines, from 0.07 (1.24 +/- 0.35 logMAR) to 0.56 (0.27 +/- 0.17 logMAR), and the mean CDVA improved by almost 3 lines, from 0.42 (0.40 +/- 0.17 logMAR) to 0.77 (0.12 +/- 0.10 logMAR). The mean K reading decreased by 5.76 D, from 48.96 D to 43.20 D. No serious intraoperative complications occurred. Side effects included glare and night-vision problems.

Conclusions: Treatment of keratoconus with ICCR implantation significantly improved visual function. The nomogram requires grading the disease using the K readings only. The UDVA and CDVA also improved during the first postoperative year.

Financial Disclosure: Drs. Mahmoud and Venkateswaran have no financial or proprietary interest in any material or method mentioned. Additional disclosure is found in the footnotes.

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http://dx.doi.org/10.1016/j.jcrs.2010.03.039DOI Listing

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