An efficient methodology taking advantage of the excellent nucleophilicity of aminoquinone to assemble the azaanthraquinone framework was developed via an iodine-induced 6-endo-dig electrophilic cyclization. Therefore, starting from N-propargylaminoquinones, various 3-iodo-1-azaanthraquinones were obtained in yields ranging from 45% to 90%. The metal-free protocol features facile installation of an iodine atom on the azaanthraquinone ring and benign functional group compatibility.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c004896h | DOI Listing |
Publication Analysis
Top Keywords
iodine-induced 6-endo-dig
8
6-endo-dig electrophilic
8
electrophilic cyclization
8
azaanthraquinone assembly
4
assembly n-propargylamino
4
n-propargylamino quinone
4
quinone iodine-induced
4
cyclization efficient
4
efficient methodology
4
methodology advantage
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!