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Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
PLoS Biol
September 2007
Department of Pediatric Pneumology and Immunology, Charité Universitätsmedizin Berlin, Germany.
Atopic dermatitis (AD) is a common chronic inflammatory skin disorder and a major manifestation of allergic disease. AD typically presents in early childhood often preceding the onset of an allergic airway disease, such as asthma or hay fever. We previously mapped a susceptibility locus for AD on Chromosome 3q21.
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