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http://dx.doi.org/10.1097/BCR.0b013e3181eed4d6 | DOI Listing |
Crit Care
December 2024
Medical Innovation Research Division and Fourth Medical Center of Chinese, PLA General Hospital, State Key Laboratory of Trauma and Chemical Poisoning, Beijing, 100853, China.
Background: Megakaryocytes are traditionally recognized as cells responsible for platelet production. However, beyond their role in thrombopoiesis, megakaryocytes also participate in inflammatory responses and regulate immune system functions. Sepsis, characterized by life-threatening organ dysfunction due to a dysregulated response to infection, prominently features coagulopathy, severe inflammation, and immune dysfunction as key pathophysiological aspects.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
January 2025
Hariram Motumal Nasta & Renu Hariram Nasta Ophthalmic Plastic Surgery Services.
Purpose: To report the long-term surgical outcomes of acquired ankyloblepharon correction using mucous membrane graft.
Methods: Five eyes of 4 patients (median age, 19 years) with acquired ankyloblepharon were managed using eyelid splitting and mucous membrane graft anchored to the recti muscles on the bulbar surface in the respective quadrant and onto the bare tarsal surface. Outcome measures include a change in the palpebral fissure width, ability to fit scleral contact lenses, visual acuity, and cosmesis.
Wound Repair Regen
December 2024
Alliance of Dutch Burn Care (ADBC), Burn Centre, Red Cross Hospital, Beverwijk, The Netherlands.
Deep dermal and full-thickness burns often result in scar sequelae such as contractures, hypertrophy, pain and itching following split-thickness skin grafting. Dermal substitutes are currently employed alongside split-thickness skin grafting to enhance clinical outcomes, though their indications remain a subject of ongoing debate. This systematic review aims to clarify the indications for the application of dermal substitutes in burn patients, in both acute and reconstructive settings.
View Article and Find Full Text PDFBurns
December 2024
Burns & Plastics Department, Salisbury NHS Foundation Trust, Odstock Road, Salisbury, Wiltshire SP2 8BJ, United Kingdom.
Adv Sci (Weinh)
December 2024
State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin, 300353, P. R. China.
Burn injuries often cause prolonged oxidative stress and inflammatory pain due to an initial increase in inflammatory responses, consequently exacerbating depressive disorders and severely impairing patients' quality of life. The primary function of traditional burn dressings is to prevent infection and facilitate tissue repair. However, these dressings are not intended for the inflammatory pain and depression that often occur during recovery.
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