The study explored the association between temperament and character and medication adherence in 76 patients with schizophrenia. Patients were assessed with the Temperament and Character Inventory, the Beck Depression Inventory, and the Positive and Negative Syndrome Scale. First-degree relatives were used as informants on adherence. The patients differed in their adherence based on the effect of gender, as males were found to be less adherent than females. Adherence differed based on novelty seeking. The temperament of the patient should be considered during the assessment of adherence.
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http://dx.doi.org/10.1016/j.psychres.2010.06.013 | DOI Listing |
Breast Cancer
December 2024
Department of Pathology, St. Luke's International Hospital, 9-1, Akashi-cho, Chuo-ku, Tokyo, 1048560, Japan.
Background: Triple-negative breast cancer (TNBC) is a serious disease with limited treatment options. We explored the significance of androgen receptor (AR) expression and tumor-infiltrating lymphocytes (TILs) in predicting neoadjuvant chemotherapy (NAC) resistance in TNBC, hypothesizing that AR/TIL classification using pretreatment biopsies can identify NAC-resistant subgroups and improve the understanding of apocrine differentiation.
Methods: This retrospective study included 156 consecutive patients with TNBC treated with NAC.
Arch Orthop Trauma Surg
December 2024
University Hospital Regensburg, Regensburg, Germany.
Introduction: Patellar fractures are rare at 1% incidence of all fractures. However, they can cause significant functional impairments due to the patella's role in knee joint extension. Current scoring systems lack objectivity in assessing patellar healing.
View Article and Find Full Text PDFPharmacy (Basel)
December 2024
R&D for Clinical Activity in Telemedicine, Italian National Health Agency-AGENAS, 00187 Rome, Italy.
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias of clinical relevance and a major cause of cardiovascular morbidity and mortality. Following a diagnosis of AF, patients are directed towards therapy with anticoagulant drugs to reduce the thromboembolic risk and antiarrhythmics to control their cardiac rhythm, with periodic follow-up checks. Despite the great ease of handling these drugs, we soon realized the need for follow-up models that would allow the appropriateness and safety of these pharmacological treatments to be monitored over time.
View Article and Find Full Text PDFPharmacy (Basel)
December 2024
Department of Applied Pharmacy, Faculty of Pharmacy, LV-1007 Riga, Latvia and Institute of Public Health, Riga Stradiņš University, LV-1010 Riga, Latvia.
Background: Valproates are recognized for their significant teratogenic risks, which can lead to physical defects and developmental disorders when used during pregnancy. To mitigate these risks, the Pregnancy Prevention Program (PPP) was developed by European regulators for patients and healthcare professionals (HCPs). Despite the crucial nature of this program, the implementation of the PPP does not appear to be fully effective.
View Article and Find Full Text PDFPharmacy (Basel)
November 2024
CBIOS-Universidade Lusófona Research Center for Biosciences and Health Technologies, Campo Grande, 376, 1749-024 Lisbon, Portugal.
Background: Patient adherence to antibiotics is vital to ensure treatment efficiency.
Objective: To evaluate the impact of pharmacist communication-based interventions on patients' adherence to antibiotics.
Methods: A systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for systematic review (PRISMA) checklist and flow diagram.
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