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Dispensing issues and disciplinary measures during opioid agonist treatment: A viewpoint.
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National Drug Dependence Treatment Center, All India Institute of Medical Sciences, New Delhi.
Opioid Use Disorder (OUD) poses a significant public health challenge globally, with an estimated 23 million opioid users in India. Opioid Agonist Therapy (OAT) stands as the cornerstone of treatment, offering potential reductions in morbidity, societal burdens, and improvements in patient quality of life. However, OAT coverage remains fairly low in India, with clinical guidelines lacking comprehensive information on implementation pragmatics.
View Article and Find Full Text PDFEfficacy and safety of larotrectinib in patients with TRK fusion gastrointestinal cancer.
Eur J Cancer
March 2025
Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Larotrectinib is the first-in-class, highly selective TRK inhibitor with demonstrated efficacy in various TRK fusion solid tumours. We report the efficacy and safety of larotrectinib in patients with TRK fusion gastrointestinal (GI) cancer.
Methods: Patients with TRK fusion GI cancer from NAVIGATE (NCT02576431) were included.
Background: Substance use among healthcare professionals is not uncommon. The challenges of seeking treatment, maintaining employment, and being in recovery are compounded by the demanding profession.
Methods: This qualitative descriptive study used interviews with substance use treatment providers in Colorado.
Why Is Social Reintegration Support for Patients With Left Ventricular Assist Device Necessary?
Circ Rep
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Department of Cardiorenal and Cerebrovascular Medicine, Faculty of Medicine, Kagawa University Kagawa Japan.
Left ventricular assist devices (LVADs) serve as critical life-sustaining therapy for patients with end-stage heart failure awaiting heart transplantation, significantly improving survival rates and enabling social reintegration. However, many patients with LVAD face multiple challenges in their daily lives and social reintegration, such as anxiety about the device, low societal awareness, and economic and psychological burdens. In Japan, where prolonged waiting periods for heart transplants are inevitable, these challenges further exacerbate the economic and psychological burdens on both patients and caregivers.
View Article and Find Full Text PDFBackground: The migration of skilled medical professionals from low- and middle-income countries, particularly when facing a shortage of physicians, negatively affects the capacity to meet essential health and social needs. This study aimed to investigate the willingness to migrate and its associated factors from the perspective of medical residents in Iran.
Methods: This multi-centric cross-sectional study was conducted in four top-ranked medical schools across Iran.
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