AI Article Synopsis
- High morbidity risks are associated with iliac crest bone graft harvesting, but using a mix of local autograft and freeze-dried allograft could lessen these risks while improving fusion rates in spinal surgeries.
- In a study involving 50 adolescent patients with idiopathic scoliosis, a combination of these grafts was used in posterior spinal fusion, and outcomes were measured through clinical assessments and a quality of life survey.
- Results showed significant improvements in spinal alignment without major complications or pseudarthrosis, suggesting this method may reduce the need for more invasive bone harvesting while effectively ensuring spinal fusion.
Article Abstract
Background: High morbidity has been reported with iliac crest bone graft harvesting; however, donor bone is typically necessary for posterior spinal fusion. Autograft bone combined with allograft may reduce the morbidity associated with iliac crest bone harvesting and improve the fusion rate. Our aim in this study was to determine the presence of complications, pseudarthrosis, non-union, and infection using combined in situ local autograft bone and freeze-dried cancellous allograft bone in patients undergoing posterior spinal fusion for the treatment of adolescent idiopathic scoliosis.
Methods: A combination of in situ local autograft bone and freeze-dried cancellous allograft blocks were used in 50 consecutive patients with adolescent idiopathic scoliosis treated by posterior fusion and Moss Miami pedicle screw instrumentation. Results were assessed clinically and radiographically and quality of life and functional outcome was evaluated by administration of a Chinese version of the SRS-22 survey.
Results: There were 41 female and 9 male patients included for analysis with an average age of 14.7 years (range, 12-17). All patients had a minimum follow-up of 18 months (range, 18 to 40 months). The average preoperative Cobb angle was 49.8 degrees (range, 40 degrees to 86 degrees ). The average number of levels fused was 9.8 (range, 6-15). Patients had a minimum postoperative follow-up of 18 months. At final follow-up, the average Cobb angle correction was 77.8% (range, 43.4 to 92.5%). There was no obvious loss in the correction, and the average loss of correction was 1.1 degrees (range, 0 degrees to 4 degrees ). There was no pseudarthrosis and no major complications.
Conclusions: In situ autograft bone combined with allograft bone may be a promising method enhances spinal fusion in AIS treated with pedicle screw placement. By eliminating the need for iliac crest bone harvesting, significant morbidity may be avoided.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928762 | PMC |
| http://dx.doi.org/10.1186/1471-2474-11-159 | DOI Listing |
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