Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/15648265100311s108 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Determining the optimal antibiotic duration for skin and soft tissue infections.
Curr Opin Infect Dis
January 2025
Department of Medicine, Clínica Rotger Quironsalud, Palma de Mallorca, Spain.
Purpose Of Review: Optimal duration of therapy in SSTIs - a heterogeneous group of infections - remains unknown. The advances in knowledge of antibiotic duration of treatment in selected SSTIs that can impact clinical practice and published in the last 18 months are reviewed.
Recent Findings: Recent evidence indicates that few patients receive guideline concordant empiric antibiotics and appropriate duration in the United States, although this likely can be extrapolated to other countries.
Synaptic cleft geometry modulates NMDAR opening probability by tuning neurotransmitter residence time.
Biophys J
January 2025
Department of Pharmacology, School of Medicine, University of California San Diego, CA 92093, USA; Department of Mechanical and Aerospace Engineering, University of California San Diego, CA 92093, USA. Electronic address:
Synaptic morphology plays a critical role in modulating the dynamics of neurotransmitter diffusion and receptor activation in interneuron communication. Central physical aspects of synaptic geometry, such as the curvature of the synaptic cleft, the distance between the presynaptic and postsynaptic membranes, and the surface area-to-volume ratio of the cleft, crucially influence glutamate diffusion and N-Methyl-D-Aspartate receptor (NMDAR) opening probabilities. In this study, we developed a stochastic model for receptor activation using realistic synaptic geometries.
View Article and Find Full Text PDFClassical and quantum states working in concert play an essential role in high-precision interferometry. In this regard, coherent combined with squeezed vacuum states are the most promising candidate. Here we complement this subject by comparing nonlinear and nonlinear-linear hybrid interferometers with homodyne detection as a readout strategy.
View Article and Find Full Text PDFSpatial accuracy of dose delivery significantly impacts the planning target volume margin in linear accelerator-based intracranial stereotactic radiosurgery.
Sci Rep
January 2025
Radiation Safety and Quality Assurance division, National Cancer Center Hospital East, Chiba, 277-8577, Japan.
The impact of three-dimensional (3D) dose delivery accuracy of C-arm linacs on the planning target volume (PTV) margin was evaluated for non-coplanar intracranial stereotactic radiosurgery (SRS). A multi-institutional 3D starshot test using beams from seven directions was conducted at 22 clinics using Varian and Elekta linacs with X-ray CT-based polymer gel dosimeters. Variability in dose delivery accuracy was observed, with the distance between the imaging isocenter and each beam exceeding 1 mm at one institution for Varian and nine institutions for Elekta.
View Article and Find Full Text PDFCross-Platform Ecological Momentary Assessment App (JTrack-EMA+): Development and Usability Study.
J Med Internet Res
January 2025
Research Centre Jülich, Institute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Jülich, Germany.
Background: Traditional in-clinic methods of collecting self-reported information are costly, time-consuming, subjective, and often limited in the quality and quantity of observation. However, smartphone-based ecological momentary assessments (EMAs) provide complementary information to in-clinic visits by collecting real-time, frequent, and longitudinal data that are ecologically valid. While these methods are promising, they are often prone to various technical obstacles.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!