Strobilols L and M, which are cadinane sesquiterpene derivatives, were isolated from the liquid culture of the edible mushroom Strobilurus ohshimae. Their structures have been established on the basis of spectral analyses. Strobilols A-M were examined for their growth inhibition activity against human cancer cell lines YMB and COLO 201.
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Species diversity, distribution patterns, and substrate specificity of Strobilurus.
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The fungal genus Strobilurus belongs to Physalacriaceae and contains approximately 11 species worldwide. Species of this genus grow and reproduce on cones of various conifers, seed pods or fruits of Magnolia and Liquidambar, and branches and wood of conifers. Previous studies focused mainly on samples from Europe and North America.
View Article and Find Full Text PDFCadinane sesquiterpenoids, strobilols L and M, from Strobilurus ohshimae.
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Department of Bioresource Engineering, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan.
Strobilols L and M, which are cadinane sesquiterpene derivatives, were isolated from the liquid culture of the edible mushroom Strobilurus ohshimae. Their structures have been established on the basis of spectral analyses. Strobilols A-M were examined for their growth inhibition activity against human cancer cell lines YMB and COLO 201.
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Four sesquiterpenoids--strobilols A (1), B (2), C (3), and D (4)--were isolated from the organic extracts of fruiting bodies of the edible mushroom Strobilurus ohshimae. Their structures were determined by spectroscopic methods. Compound 1 exhibited moderate activity against the brine shrimp Artemia salina.
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