Thermodynamic Origin of Prolyl Peptide Bond Isomers.

Tetrahedron Lett

Department of Biochemistry, University of Wisconsin, Madison, WI 53706-1569 USA.

Published: May 1993

The thermodynamic preference for the trans isomer of prolyl peptide bonds arises almost entirely from enthalpy in aqueous buffer and in toluene.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902179PMC
http://dx.doi.org/10.1016/S0040-4039(00)93377-XDOI Listing

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