We use a simple model of micro-vascular blood flow to explore conditions that give rise to multiple equilibrium states in a three-node micro-vascular network. The model accounts for two primary rheological effects: the Fåhraeus-Lindqvist effect, which describes the apparent viscosity of blood in a vessel, and the plasma skimming effect, which governs the separation of red blood cells at diverging nodes. We show that multiple equilibrium states are possible, and we use our analytical and computational tools to design an experiment for validation.
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http://dx.doi.org/10.1016/j.mbs.2010.07.001 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
Department of Chemical Engineering, University of Patras, Patras 26504, Greece.
Energy-efficient separation of light alkanes from alkenes is considered as one of the most important separations of the chemical industry today due to the high energy penalty associated with the applied conventional cryogenic technologies. This study introduces fluorine-doped activated carbon adsorbents, where elemental fluorine incorporation into the carbon matrix plays a unique role in achieving high ethane selectivity. This enhanced selectivity arises from specific interactions between surface-doped fluorine atoms and ethane molecules, coupled with porosity modulation.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education, School of Chemical Engineering, Xinjiang University, Urumqi 830017, China.
Lead (Pb) is classified as a prevalent metallic pollutant, significantly impacting the ecological environment, especially human health. Consequently, it is crucial to develop adsorbent materials that are environmentally friendly, cost-effective, and which possess high selectivity. This study aims to fabricate a Pb(II)-imprinted acrylonitrile-co-acrylic acid composite material by using modified sand particles as the carrier, and then to investigate its properties.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Graduate School of Science and Engineering, Ibaraki University, 4-12-1 Nakanarusawa, Hitachi 316-8511, Ibaraki, Japan.
The sintered diffusion multiple (SDM) method, which has been developed in our research group, has been applied to determine the entire composition range of the CrMnFeCoNi high-entropy alloy stereoscopically and continuously over nearly the entire range. The samples were prepared by sintering mixed elemental powders and were annealed at 970 °C or 800 °C. Several hundreds of thousands of points were analyzed at random within the samples for chemical compositions using electron probe microanalysis.
View Article and Find Full Text PDFFront Pharmacol
January 2025
Department of Cardiovascular Center, First Affiliated Hospital of Huzhou University, Huzhou, China.
The emergence of targeted anti-tumor drugs has significantly prolonged the lifespan and improved the prognosis of cancer patients. Among these drugs, vascular endothelial growth factor (VEGF) inhibitors, particularly novel small molecule tyrosine kinase inhibitors (TKIs), are extensively employed as VEGF inhibitors; however, they are also associated with a higher incidence of complications, with hypertension being the most prevalent cardiovascular toxic side effect. Currently, it is widely accepted that TKIs-induced hypertension involves multiple mechanisms including dysregulation of the endothelin (ET) axis, reduced bioavailability of nitric oxide (NO), imbalance in NO-ROS equilibrium system, vascular rarefaction, and activation of epithelial sodium calcium channels; nevertheless, excessive activation of ET system appears to be predominantly responsible for this condition.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Key Laboratory of Intelligent Supramolecular Chemistry at the University of Yunnan Province, National and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, School of Chemistry & Environment, Yunnan Minzu University, Kunming 650500, P. R. China.
Developing efficient and recyclable iodine adsorbents is crucial for addressing radioactive iodine pollution. An imidazole cation-bridged pillar[5]arene polymer (P5-P5I) was synthesized via a salt formation reaction. P5-P5I exhibited a high iodine vapor capture capacity of 2130.
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