Purpose: The aim of this retrospective study was to compare the frequency of spontaneous early exposure of cover screws and marginal bone resorption in conventionally and early-placed submerged implants before second-stage surgery.
Materials And Methods: A total of 103 Nobel Biocare Branemark implants were conventionally (Group 1), or early-placed (Group 2) in 46 consecutive patients following the two-stage surgical protocol. Patients in both groups received oral hygiene training in self-performed plaque control measures, including exposure of cover screws during healing. Spontaneous cover screw exposure (CSE) of each implant was recorded for both groups and scored from Class 0 (no perforation) to Class 4 (complete exposure). Plaque index scores were recorded and marginal bone-level (MBL) changes were measured in radiographs before second-stage surgery in a blind manner.
Results: MBL in Group 2 was higher than Group 1 in patients with or without interim prosthesis (P<0.05). The use of interim prosthesis did not increase MBL in Group 1, but led to higher MBL in Group 2. The percentage of non-exposed implants in Group 1 was higher than Group 2 (P=0.007, odds ratio=7). Group 1 implants had 11.5 times greater plaque index score 0 than those in Group 2 (P=0.031, odds ratio=11.5). The differences between MBL with regard to CSE scores 0 and 1-4 was significant for both sides in Group 2 and the mesial side in Group 1 (P<0.05). The difference between MBL with regard to plaque index scores 1-3 was similar in both groups (P>0.05).
Conclusions: There is a direct relation between spontaneous early cover screw perforations with early crestal bone loss. Early-placed implants experienced more spontaneous perforations and associated bone loss in comparison with conventionally placed submerged implants. The use of interim dentures may lead to more CSE and consequent MBL in the early-placement protocol.
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http://dx.doi.org/10.1111/j.1600-0501.2010.01952.x | DOI Listing |
Alzheimers Dement
December 2024
Department of Psychology, University of Toronto, Toronto, Ontario, Canada.
Introduction: Women with early bilateral salpingo-oophorectomy (BSO) have greater Alzheimer's disease (AD) risk than women with spontaneous menopause (SM), but the pathway toward this risk is understudied. Considering associative memory deficits may reflect early signs of AD, we studied how BSO affected brain activity underlying associative memory.
Methods: Early midlife women with BSO (with and without 17β-estradiol therapy [ET]) and age-matched controls (AMCs) with intact ovaries completed a face-name associative memory task during functional magnetic resonance imaging.
Int J Gynaecol Obstet
December 2024
Department of Obstetrics and Gynecology, Nord Hospital, APHM, Chemin Des Bourrely, Marseille, France.
Objective: This study investigates whether early gestational age (GA) at delivery is associated with an increased risk for severe maternal morbidity (SMM) in women with preterm delivery.
Methods: This retrospective national cohort study based on the Programme de Médicalisation des Systèmes d'Information database included mothers who gave birth between 22 and 37 weeks in metropolitan France in 2019 (in utero deaths and medical terminations of pregnancies were excluded). SMM was defined as a composite criterion consisting of the occurrence of at least one of the following events: death, severe preeclampsia, obstetric surgical complications, severe maternal diseases, and admission to the intensive care unit.
JAMA Netw Open
December 2024
Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California.
Importance: Serial circulating tumor DNA (ctDNA) has emerged as a routine surveillance strategy for patients with resected colorectal cancer, but how serial ctDNA monitoring is associated with potential curative outcomes has not been formally assessed.
Objective: To examine whether there is a benefit of adding serial ctDNA assays to standard-of-care imaging surveillance for potential curative outcomes in patients with resected colorectal cancer.
Design, Setting, And Participants: In this single-center (City of Hope Comprehensive Cancer Center, Duarte, California), retrospective, case cohort study, patients with stage II to IV colorectal cancer underwent curative resection and were monitored with serial ctDNA assay and National Cancer Center Network (NCCN)-guided imaging surveillance from September 20, 2019, to April 3, 2024.
Cureus
November 2024
Department of Pathology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed To Be University), Karad, IND.
Introduction Hypothyroidism represents an endocrine disorder marked by the insufficient production of hormones by the thyroid gland, with significant effects on bodily functions. Its occurrence during pregnancy is of particular concern due to its profound effects on both maternal and fetal health outcomes. Aim To study the impact of hypothyroidism in pregnancy and its correlation with feto-maternal outcomes.
View Article and Find Full Text PDFJA Clin Rep
December 2024
Department of Anesthesiology, Niigata University Medical and Dental Hospital, 1-754 Asahimachi-Dori, Chuo-Ku, Niigata, 951-8520, Japan.
Background: Non-ketotic hyperglycinemia (NKH) is a rare autosomal recessive disorder caused by defects in the glycine cleavage system, leading to elevated glycine levels in the central nervous system. NKH manifests in various forms, with the neonatal type being the most severe and often associated with high mortality and significant neurological impairment. This case report highlights the successful uses of desflurane and nitrous oxide for anesthetic management in a patient with NKH.
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