AI Article Synopsis
- The study aimed to investigate factors related to the presence of HSV-1 antibodies and check for HSV-1 in genital samples.
- A total of 815 students participated, revealing a 56.7% seroprevalence of IgG antibodies for HSV-1, with higher rates linked to sexual behaviors like having multiple partners or engaging in sex work.
- Although 18.2% tested positive for IgM antibodies, no genital samples showed the presence of HSV-1 DNA, suggesting that while HSV-1 might spread through sexual contact, it wasn't found in the analyzed samples, indicating a need for further research in high-risk populations.
Article Abstract
Objective: To study the factors associated with the presence of antibodies against herpes simplex virus type 1 (HSV-1) and to screen for HSV-1 in genital samples.
Materials And Methods: Students answered a survey and provided biological samples (blood and genital discharge). The detection of IgG and IgM antibodies against HSV-1 was performed by an ELISA test. From IgM positive samples we sought and extracted genital DNA and identified a beta-globulin gene and HSV-1.
Results: Eight hundred and fifteen students participated. IgG/HSV-1 seroprevalence was 56.7%, HSV-1 infection was associated with number of sexual partners, exchanging sex for money, same sex relationships and occasional partners. IgM/HSV-1 seroprevalence was 18.2%, 91 samples were positive for human beta-globuline but none for HSV-1 DNA.
Conclusions: Epidemiological evidence suggests that HSV-1 could be transmitted by sexual contact among college students; however, HSV-1 was not detected in any of the genital samples analyzed. To further test our hypothesis we need to study HSV-1 among high risk groups or increase our sample size.
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