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Clinical and Hematological Characteristics of Vitamin B12 Deficiency and Evaluation of the Therapeutic Response to Vitamin B12 Supplementation.
Cureus
December 2024
Research and Development, MediBrains Social Welfare Foundation, Mumbai, IND.
Background Vitamin B12 deficiency, or cobalamin deficiency, is common among populations with low consumption of animal-based products, mainly in India, due to religious and socioeconomic factors, which significantly increase the deficiency rate. The condition has been characterized by a wide range of clinical and hematological symptoms, mainly affecting the blood and nervous system. This study aims to assess the clinical and hematological characteristics of patients with vitamin B12 deficiency and assess the therapeutic response to supplementation with vitamin B12.
View Article and Find Full Text PDFWhat is the origin of the normal ranges of blood cell counts? An evolutionary perspective.
EJHaem
February 2025
Centre International de Recherche en Infectiologie (CIRI, INSERM U1111, CNRS UMR 5308, École Normale supérieure de Lyon) Lymphoma ImmunoBiology team Faculté de Médecine Lyon sud Université Claude Bernard Lyon 1 Lyon France.
Background: The normal values of the complete blood count are part of the foundational medical knowledge that is seldom questioned due to their well-established nature. These normal values are critical for optimal physiological function while minimizing the harmful consequences of an excessive number of blood cells. Thus, they represent an evolutionary trade-off likely shaped by natural selection if they significantly influence individual fitness and exhibit heritability.
View Article and Find Full Text PDFThe Treatment Experiences of Vegetarians and Vegans with an Eating Disorder: A Qualitative Study.
Nutrients
January 2025
Department of Psychology, Counselling, and Therapy, La Trobe University, Melbourne, VIC 3083, Australia.
Background: Vegetarianism and veganism have long been tied to disordered eating and are frequently considered to be methods of limiting available food choices. Health professionals specializing in eating disorder treatment may modify their treatment practices to support their vegetarian or vegan clients. However, there are no formally recognized clinical guidelines for the treatment of eating disorders in these groups.
View Article and Find Full Text PDFExploring Nutrient-Adequate Sustainable Diet Scenarios That Are Plant-Based but Animal-Optimized.
Nutrients
January 2025
Nederlandse Zuivel Organisatie (NZO), 2596 BC The Hague, The Netherlands.
: Transitions toward more sustainable food systems may become rather polarized, particularly in the plant-based vs. animal-based debate. These discussions, however, are often based on environmental impact data from individual products or product groups and do not consider that the products together should form a nutrient-adequate diet that is also affordable.
View Article and Find Full Text PDFImpact of the Healthy Lifestyle Community Program (HLCP-3) on Trimethylamine N-Oxide (TMAO) and Risk Profile Parameters Related to Lifestyle Diseases During the Six Months Following an Intervention Study.
Nutrients
January 2025
Department of Nutrition, University of Applied Sciences Münster (FH), 48149 Münster, Germany.
Rationale: The dietary components choline, betaine, and L-carnitine are converted by intestinal microbiota into the molecule trimethylamine (TMA). In the human liver, hepatic flavin-containing monooxygenase 3 oxidizes TMA to trimethylamine-N-oxide (TMAO). TMAO is considered a candidate marker for the risk of cardiovascular disease.
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