Hydrogels are recognized as the standard treatment for necrotic or sloughy wounds. Autolytic debridement of devitalized tissue is essential to promote wound healing; this depends on the whole area being kept moist so that natural enzymatic reactions can take place. Hydrogels are considered to be gentle debriders, promoting rehydration of non-viable tissues. Hydrosorb and Hydrosorb Comfort are hydrocellular gel dressings that are made from 60% water and are therefore suitable for keeping granulation tissue and young epithelium moist. Additionally, Hydrosorb provides a cushioning effect for wound protection, and has a soothing and cooling effect on superficial burns. For some patients with burns, such as the elderly, Hydrosorb can be applied to speed up the process of debridement where surgery is not an option; a case study is given to show the effective healing process.
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http://dx.doi.org/10.12968/bjon.2010.19.Sup4.48419 | DOI Listing |
PLoS One
January 2025
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, United States of America.
The extrusion bioprinting of collagen material has many applications relevant to tissue engineering and regenerative medicine. Freeform Reversible Embedding of Suspended Hydrogels (FRESH) technology is capable of 3D printing collagen material with the specifications and details needed for precise tissue guidance, a crucial requirement for effective tissue repair. While FRESH has shown repeated success and reliability for extrusion printing, the mechanical properties of completed collagen prints can be improved further by post-print crosslinking methodologies.
View Article and Find Full Text PDFACS Biomater Sci Eng
January 2025
Chongqing Key Laboratory of Reproductive Health and Digital Medicine, Department of Laboratory Medicine, Chongqing General Hospital, School of Medicine, Chongqing University, Chongqing 401147, China.
Diabetes exacerbates periodontitis by overexpressing reactive oxygen species (ROS), which leads to periodontal bone resorption. Consequently, it is imperative to relieve inflammation and promote alveolar bone regeneration comprehensively for the development of diabetic periodontal treatment strategies. Furthermore, an orderly treatment to avoid interference between these two processes can achieve the optimal therapeutic effect.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Department of Chemistry and Material Engineering, Lyuliang University, Lyuliang, 033000, P. R. China.
Innovative double-emission carbon dots (DE-CDs) were synthesized via a one-step hydrothermal method using fennel and m-phenylenediamine (m-PD) as precursors. These DE-CDs exhibited dual emission wavelengths at 432 and 515 nm under different excitations, making them highly versatile for fluorescence-based applications. The fluorescence of the DE-CDs was efficiently quenched by tetracycline (TC) through the inner filter effect (IFE), allowing for the construction of a sensitive dual-response fluorescent sensor.
View Article and Find Full Text PDFAdv Healthc Mater
January 2025
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, 210094, China.
Effective treatment of bone diseases is quite tricky due to the unique nature of bone tissue and the complexity of the bone repair process. In combination with biological materials, cells and biological factors can provide a highly effective and safe treatment strategy for bone repair and regeneration, especially based on these multifunctional hydrogel interface materials. However, itis still a challenge to formulate hydrogel materials with fascinating properties (e.
View Article and Find Full Text PDFMater Today Bio
February 2025
Department of Orthopedics, the Fourth Medical Center of PLA General Hospital, Beijing, 100048, PR China.
A meniscus injury is a common cartilage disease of the knee joint. Despite the availability of various methods for the treatment of meniscal injuries, the poor regenerative capacity of the meniscus often necessitates resection, leading to the accelerated progression of osteoarthritis. Advances in tissue engineering have introduced meniscal tissue engineering as a potential treatment option.
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