Type II endoleaks occur in 5% to 10% of patients who are treated by endovascular aneurysm repair. A persistent type II endoleak combined with documented aneurysm expansion is generally considered an indication for intervention. Thrombin injection directly into the aneurysm sac is described as a safe and efficient treatment option. We present a patient with a ruptured aneurysm caused by a puncture of the stent graft during computed tomography-guided thrombin injection. This case highlights a possible harmful complication of thrombin injection and emphasizes the need for caution while performing such a procedure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jvs.2010.04.074 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Balloon-assisted percutaneous thrombin injection in a subclavian artery pseudoaneurysm: A case report.
Radiol Case Rep
March 2025
Department of Medical Imaging, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia.
Subclavian artery pseudoaneurysm (SAP) is a rare but lethal diagnosis, and an important condition that should be detected and managed imperatively. SAP has been seldom described in the literature, explaining the lack of concrete management guidelines. Herein we present a case study of a 63-year-old man with SAP post a transcatheter aortic valve implantation (TAVI) done 8 days prior to current presentation.
View Article and Find Full Text PDFBrolucizumab and Platelet Activation and Reactivity.
Curr Eye Res
January 2025
Centre for Ophthalmology, Eberhard-Karls University, Tübingen, Germany.
Purpose: This study explores the potential interaction of brolucizumab with platelets and its effects on platelet activation and reactivity, crucial in retinal vasculitis and retinal vascular occlusion. Safety concerns remain of interest, although brolucizumab showed superior retinal efficacy and reduced injection frequency compared to other licensed anti-VEGF agents.
Methods: Resting and activated platelets of healthy volunteers were pretreated with brolucizumab at the following concentrations 0.
[Effect of balloon occlusion combined with intra-sac injection of thrombin in the treatment of ruptured abdominal aortic aneurysm].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Objective: To investigate the safety and effectiveness of balloon occlusion and intra-sac thrombin injection in the endovascular repair of ruptured abdominal aortic aneurysm.
Methods: From October 2019 to October 2022, the clinical data of 16 patients with rAAA treated with balloon occlusion technique and intra-sac thrombin injection combined with EVAR were retrospectively analyzed, including 13 males and 3 females, aged 42-85 years, with a median age of 70.5 years.
Management of patients developing axillary pseudoaneursym after ductal stenting: Report of three cases.
Turk Gogus Kalp Damar Cerrahisi Derg
October 2024
Department of Pediatric Cardiology, University of Health Sciences, Başakşehir Çam ve Sakura City Hospital, Istanbul, Türkiye.
Pseudoaneurysms develop as a result of disruption of the arterial wall due to trauma or iatrogenic reasons such as catheterization, and it is important due to the high risk of bleeding and rupture. Until recently, the main treatment of pseudoaneurysms was surgical repair. However, in recent years, minimally invasive methods such as ultrasound-guided compression and percutaneous thrombin injection have been used more frequently.
View Article and Find Full Text PDFBidirectional Enzyme Inhibition and Activation for In Situ Formation of Injectable Hydrogel Using a Bispecific Aptamer.
Langmuir
December 2024
Department of Biomedical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Article Synopsis
- - The study focuses on in situ injectable hydrogels, which are important for applications in regenerative medicine and drug delivery, but face challenges in controlling gelation speed for easier injection.
- - Researchers investigated a system using bispecific aptamers that can inhibit thrombin (an enzyme involved in clotting) to slow down the formation of fibrin hydrogels.
- - The study found that when these aptamers interacted with complementary sequences, they could reverse the inhibition, speeding up the hydrogel formation process, demonstrating a new dynamic control for enzyme-mediated hydrogel development.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!