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Machine learning-derived multivariable predictors of postcardiotomy cardiogenic shock in high-risk cardiac surgery patients.
JTCVS Open
December 2024
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Objective: To develop a model for preoperatively predicting postcardiotomy cardiogenic shock (PCCS) in patients with poor left ventricular (LV) function undergoing cardiac surgery.
Methods: From the Society of Thoracic Surgeons Adult Cardiac Database, 11,493 patients with LV ejection fraction ≤35% underwent isolated on-pump surgery from 2018 through 2019, of whom 3428 experienced PCCS. In total, 68 preoperative clinical variables were considered in machine-learning algorithms trained and optimized using scikit-learn software.
Comparative Analysis of Irrigation Mist and CO vs. Direct CO Blower in On-Pump Coronary Artery Bypass Grafting Anastomosis: Efficacy, Efficiency, and Fibrillation upon De-Clamping and Micro-Embolic Gas Activity Incidence.
Medicina (Kaunas)
December 2024
Department of Cardiac Surgery, Anthea Hospital GVM Care and Research, Via Camillo Rosalba 35/37, 70124 Bari, Italy.
In coronary artery bypass grafting (CABG) on pump, achieving optimal visualization is critical for surgical precision and safety. The use of blowers to clear the CABG anastomosis poses risks, including the formation of micro-embolic gas bubbles, which can be insidious and increase the risk of cerebral or myocardial complications. This retrospective study compares the effectiveness of the use of irrigation mist and CO versus a direct CO blower without irrigation in terms of visualization, postoperative fibrillation, and micro-embolic gas activity.
View Article and Find Full Text PDFREmoval of cytokines during CArdiac surgery (RECCAS): a randomised controlled trial.
Crit Care
December 2024
Department of Anaesthesiology, Intensive Care Medicine and Pain Medicine, Medical Faculty of Ruhr-University Bochum, BG University Hospital Bergmannsheil gGmbH, Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany.
Background: Cardiopulmonary bypass (CPB) triggers marked cytokine release often followed by a systemic inflammatory response syndrome, associated with adverse postoperative outcomes. This trial investigates the intraoperative use of haemoadsorption (HA) during cardiac surgery with CPB to assess its impact on postoperative systemic inflammatory response.
Methods: In this prospective randomised controlled trial (ethics approval no.
Prolonged time from cross clamp until normothermic machine perfusion start is associated with increased risk of early allograft dysfunction following DCD liver transplant.
Liver Transpl
December 2024
Department of Transplant, Mayo Clinic Florida, Jacksonville, Florida.
Introduction: There is a paucity of data on the impact of cold ischemia time prior to the initiation of normothermic machine perfusion (NMP), particularly in more susceptible organs such livers from DCD donors. The present analysis aimed to investigate the impact of prolonged time from cross clamp until NMP start on early allograft dysfunction (EAD) and other peri-liver transplant (LT) outcomes.
Materials: All DCD LT performed and placed on NMP at Mayo Clinic Arizona, Florida and Rochester from January 2022-March 2024 were included.
Melatonin ameliorates inflammation and improves outcomes of ischemia/reperfusion injury in patients undergoing coronary artery bypass grafting surgery: a randomized placebo-controlled study.
Apoptosis
December 2024
Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Ankara Street, Sheraton buildings, Cairo, 11566, Egypt.
To investigate the protective role of high dose melatonin concerning myocardial I/R injury and inflammation in patients undergoing on-pump coronary artery bypass grafting (CABG) surgery by evaluating IR/inflammatory biomarkers and clinical outcomes. This was a prospective; randomized; single-blinded placebo-controlled study conducted at cardio-thoracic surgery department of the Academy of the Cardiovascular and Thoracic Surgery, Ain Shams University. Eligible patients were randomly allocated to; melatonin-treated group (MTG) or placebo-treated group (PTG).
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