A 68-year-old woman, suffering from dyspnea on exertion, was admitted to our hospital. She had noticed her nails become yellow 8 years previously. She had mild bilateral effusion. Examination of the pleural fluid revealed exudates which were lymphocyte-rich, a high concentration of adenosine deaminase (ADA) and elevated serum levels of soluble interleukin-2 receptors. These confirmed the diagnosis of yellow nail syndrome.

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