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A randomized controlled study to evaluate the cost-effectiveness in sperm extraction using carbon dioxide and carbon dioxide free system in relation to intrauterine insemination pregnancy. | LitMetric

A randomized controlled study to evaluate the cost-effectiveness in sperm extraction using carbon dioxide and carbon dioxide free system in relation to intrauterine insemination pregnancy.

J Hum Reprod Sci

Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Kasturba Medical College, Manipal University, Manipal-576104 Karnataka, India.

Published: January 2010

AI Article Synopsis

  • The study evaluated the effectiveness of two sperm extraction systems—circulating water bath and CO(2) incubator—for intrauterine insemination (IUI) in a fertility clinic.
  • Sixty-two patients undergoing ovulation induction were randomly assigned to either the water bath or CO(2) incubator group to assess sperm quality and pregnancy outcomes.
  • Results indicated no significant difference in sperm quality or pregnancy rates between the two systems, suggesting that a CO(2)-free method might be a cost-effective alternative without compromising results.

Article Abstract

Objectives: To evaluate the effectiveness of two different systems i.e. circulating water bath and carbon dioxide (CO(2)) incubator in extracting motile sperm for IUI programme and their effect on pregnancy outcome.

Methods: The study was performed on sixty-two patients recruited for ovulation induction followed by intrauterine insemination (IUI) in University fertility clinic. The patients were randomly divided into two groups and sperm preparation was performed with either water bath or CO(2) incubator system. The efficiency of the two systems was analyzed in relation to pregnancy outcome.

Results: There was no significant difference in the efficacy of water bath and CO(2) system with respect to the quality of sperm extracted and pregnancy outcome. Although pregnancy rate was marginally higher in water bath group, it was not statistically significant.

Conclusion: CO(2)-free system can be a cost-effective approach in IUI programme which does not compromise with pregnancy rate.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890902PMC
http://dx.doi.org/10.4103/0974-1208.63114DOI Listing

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