AI Article Synopsis
- DNA sequencing has rapidly advanced over the past 30 years, becoming a crucial tool in biomedical research and branching into engineering and physical sciences.
- The review discusses the technical features of next-gen sequencers and predicts future developments that could make genomic sequencing much more affordable, aiming for $1000 and eventually $100 genomes.
- It emphasizes the importance of Chinese scientists' involvement in this effort, which could significantly influence both scientific progress and healthcare systems worldwide.
Article Abstract
As one of the most powerful tools in biomedical research, DNA sequencing not only has been improving its productivity in an exponential growth rate but also been evolving into a new layout of technological territories toward engineering and physical disciplines over the past three decades. In this technical review, we look into technical characteristics of the next-gen sequencers and provide prospective insights into their future development and applications. We envisage that some of the emerging platforms are capable of supporting the $1000 genome and $100 genome goals if given a few years for technical maturation. We also suggest that scientists from China should play an active role in this campaign that will have profound impact on both scientific research and societal healthcare systems.
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| http://dx.doi.org/10.1007/s11427-010-0023-6 | DOI Listing |
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