Sclerosants: a comparative review.

Dermatol Surg

Department of Medicine, Division of Dermatology, University of Southern California, Los Angeles, California, USA.

Published: June 2010

Background: Sclerotherapy is popular for the treatment of lower extremity telangiectasias and varicose and reticular veins. Although a large number of sclerosants are commonly employed, there are few data that directly compare their advantages and drawbacks.

Objectives: To analyze and present the differences between sclerosants that make them more or less suitable agents in specific clinical applications.

Materials And Methods: A systemic review of published medical literature that compares and contrasts different classes of sclerosants is presented.

Results: There is no perfect sclerosant that is complication free and 100% effective. The ability to match the sclerosant to the clinical problem being approached makes the availability of more Food and Drug Administration-approved sclerosants appealing.

Conclusion: Modern sclerosants that have been subjected to rigorous experimental and clinical trials will provide even more efficacious and safer patient treatments.

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http://dx.doi.org/10.1111/j.1524-4725.2009.01469.xDOI Listing

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