Data on 503 students from rural and urban areas were collected from January 2009 to October 2009 to test for cross-addiction of alcohol dependency with disordered gambling among college athletes and nonathletes. To test for alcohol dependency, the Michigan Alcohol Screening Test (MAST) was employed, while the South Oaks Gambling Screen (SOGS) was utilized to assess gambling behaviors. Athletes had higher frequencies of cross-addiction. For athletes there was a correlation between scores on the MAST and SOGS. Limitations related to data collection are discussed. Recommendations for further research directed toward the development of programs geared to assist students are given.
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http://dx.doi.org/10.3109/10826081003682297 | DOI Listing |
Comput Biol Chem
December 2024
Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, Guangdong Pharmaceutical University, Guangzhou 510006, PR China. Electronic address:
In the present study, we uncovered and validated potential biomarkers related to gout, characterized by the accumulation of sodium urate crystals in different joint and non-joint structures. The data set GSE160170 was obtained from the GEO database. We conducted differential gene expression analysis, GO enrichment assessment, and KEGG pathway analysis to understand the underlying processes.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Yale University, New Haven, CT, USA.
Background: Alcohol Use Disorder (AUD) affects over 15 million individuals in the United States, contributing to oxidative stress, neuroinflammation, and elevating the risk of neurodegeneration. Despite this, the connection between AUD and aging conditions, particularly Alzheimer's disease (AD), remains unclear. AD, with a heritability of 60-80%, is genetically linked, necessitating an exploration of the molecular implications of AUD and genetic susceptibility to AD.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Neurogenomics & Informatics Center, St. Louis, MO, USA.
Background: Clear sex differences exist in AD and PD. Several studies examined genetic regulations for AD phenotypes and gene expression data in a sex-specific manner, identifying some differences between males and females. In contrasts, although proteins are final effectors of most physiological pathways and important drug targets, sex-specific regulations for proteins remain vastly understudied.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Ontario Shores Centre for Mental Health Sciences, Whitby, ON, Canada.
Background: Previous literature has highlighted that excessive alcohol use (EAU) is directly linked with permanent neurological damage. Studies have also highlighted gradual improvements in heart rate variability (HRV) after cessation of alcohol use. Moreover, chronic alcohol consumption has also been correlated with reduced HRV and an increase in skin conductance (SC) among healthy adults, leading to a combined decline in cognitive performance.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California, San Diego, La Jolla, CA, USA.
Background: Neurocognitive health is influenced by multiple modifiable and non-modifiable lifestyle factors. Machine learning tools offer a promising approach to better understand complex models of cognitive function. We used extreme gradient boosting (XG Boost), an algorithm of decision-tree modeling, to analyze the association between 15 late-life lifestyle and demographic factors with episodic memory performance.
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