Importance of screening serological examination of umbilical blood and the blood of the mother for timely diagnosis of congenital toxoplasmosis and toxocariasis.

Neuro Endocrinol Lett

University of South Bohemia in Ceské Budejovice, Faculty of Health and Social Studies, Department of Clinical Branches, Ceské Budejovice, Czech Republic.

Published: October 2010

Objective: Parasitic diseases, particularly the congenital form of toxoplasmosis, can negatively affect the mortality and morbidity of newborns and infants.

Methods: The authors examined 152 samples of umbilical blood in 152 women who had experienced premature delivery with or without PROM. The samples were examined for the titre of antibodies - the CFR, levels of immunoglobulins IgA and IGM (toxoplasmosis) and for titres of antibodies against toxocariasis.

Results: No presence of IGM was demonstrated in association with the congenital form of toxoplasmosis. The values of titres of antibodies against toxocariasis were negative. There was only one case of a titre in a newborn higher than that in the mother. There was no clinical manifestation of the disease.

Conclusion: In spite of the negative result, the authors point out the possibility of a timely diagnosis of these parasitic diseases.

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